{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:30:43Z","timestamp":1747150243611,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T00:00:00Z","timestamp":1708300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR\u2010112\u2010208"],"award-info":[{"award-number":["DMR\u2010112\u2010208"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The efficacy of adjuvant sublingual immunotherapy (SLIT) in correcting structural problems in patients with allergic rhinitis (AR) caused by mite who have undergone septomeatoplasty (SMP) has not been studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This non\u2010randomized controlled study recruited patients with AR (caused by mite) and concurrent septal deviation and inferior turbinate hypertrophy, at a tertiary hospital in Taiwan. SMP was performed on all patients as a surgical intervention. The patients were then divided into two groups: the control group, which underwent surgery only, and the experimental group, which received SLIT as an adjuvant treatment. Demographic data and rhinitis control assessment test (RCAT) results were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 96 patients were enrolled in the study (SMP\u2009+\u2009SLIT group, <jats:italic>n<\/jats:italic>\u2009=\u200952; SMP only group, <jats:italic>n<\/jats:italic>\u2009=\u200944). No significant differences were observed in any of the variables between the two groups before and one month after surgery. However, during evaluations at the third and sixth month, the SMP\u2009+\u2009SLIT group showed significant improvement in the total RCAT scores compared to the SMP only group (28.6\u2009\u00b1\u20091.56 vs. 24.5\u2009\u00b1\u20093.66, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001; 27.1\u2009\u00b1\u20092.87 vs. 19.9\u2009\u00b1\u20095.56, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In addition, significantly better control of all RCAT sub\u2010categories was observed in the SMP\u2009+\u2009SLIT group at the third and sixth month evaluations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SLIT may serve as an ideal adjuvant therapy after SMP in patients with AR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 134:3073\u20133079, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31347","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T11:48:30Z","timestamp":1708343310000},"page":"3073-3079","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Adjuvant Sublingual Immunotherapy After Septomeatoplasty"],"prefix":"10.1002","volume":"134","author":[{"given":"Bing\u2010Han","family":"Hsieh","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery China Medical University Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Chun","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery China Medical University Hospital  Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su\u2010Boon","family":"Yong","sequence":"additional","affiliation":[{"name":"Center for Allergy, Immunology, and Microbiome (A.I.M.) 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