{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:41:36Z","timestamp":1792201296875,"version":"4.4.0"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the techniques and outcomes of virtual reality (VR) and mixed reality (MR)\u2010assisted powered endoscopic dacryocystorhinostomy (DCR) in extremely complex lacrimal drainage obstructions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective, non\u2010randomized clinical study was performed in complex syndromic congenital nasolacrimal duct obstruction (CNLDO) and post\u2010traumatic secondary acquired lacrimal duct obstruction (SALDO) in the setting of Le Fort fractures. All patients underwent preoperative planning in VR and intraoperative planning with a step ahead with MR assistance during the surgery. Surgery was supported by mixed reality intraoperative guidance with the use of the prearranged 3D models and real\u2010time\u2010rendered digital models. Parameters assessed include demographics, clinical presentation, complexities of the nasolacrimal duct obstruction, preoperative and intraoperative utility of VR and MR models, surgical techniques, complications, and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The technique is described as a proof of concept in challenging situations with Apert syndrome and traumatic SALDOs with gross malposition of the sac, and gross nasal and lacrimal anatomical deformities. The VR models helped the surgeon to assess the details of the altered anatomy preoperatively to plan an appropriate approach. Intraoperatively, MR models were present in the surgeon's view without disturbing the endoscopic procedure. Intermittently, the surgeon could pull any of the models virtually present in the operating room, slice them, rotate them, and intricately study the alterations in a stepwise manner, as the surgery proceeds.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Virtual reality and mixed reality\u2010assisted powered endoscopic DCR can be an alternate approach reserved for extremely challenging cases of complex syndromic CNLDOs and post\u2010traumatic SALDOs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:3508\u20133515, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31399","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T05:49:00Z","timestamp":1711000140000},"page":"3508-3515","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Virtual Reality and Mixed <scp>Reality\u2010Assisted<\/scp> Endoscopic <scp>DCR<\/scp> in Extremely Complex Lacrimal Obstructions"],"prefix":"10.1002","volume":"134","author":[{"given":"Rafal","family":"Nowak","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Military Institute of Medicine\u2010National Research Institute  Warsaw Poland"},{"name":"Department of Ophthalmology Jozef Strus City Hospital  Poznan Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabela","family":"Nowak\u2010Gospodarowicz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Military Institute of Medicine\u2010National Research Institute  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"R\u0119kas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Military Institute of Medicine\u2010National Research Institute  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6363-9202","authenticated-orcid":false,"given":"Mohammad J.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Military Institute of Medicine\u2010National Research Institute  Warsaw Poland"},{"name":"Govindram Seksaria Institute of Dacryology L.V. Prasad Eye Institute  Hyderabad India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1305757"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.07.022"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1227510"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2023.07.001"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000009794"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12909-023-04806-z"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/15533506231211844"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-5442-6_36"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000502"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2017.1280059"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2016.10.012"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-99-1401-2_86-2"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000102"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.31399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T16:12:15Z","timestamp":1760199135000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.31399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,21]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/lary.31399"],"URL":"https:\/\/doi.org\/10.1002\/lary.31399","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,21]]},"assertion":[{"value":"2024-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}