{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:02:48Z","timestamp":1793070168588,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T00:00:00Z","timestamp":1717459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>This study describes patient\u2010reported outcome measures (PROMs) and associated factors in patients who underwent surgery for malignant parotid tumors (MPT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study of all surgically treated MPT patients in a multidisciplinary head and neck cancer (HNC) survivorship clinic (2017\u20132023). PROMs included University of Washington Quality of Life Questionnaire (UW\u2010QOL), Eating Assessment Tool (EAT\u201010), Patient Health Questionnaire (PHQ\u20108), Generalized Anxiety Disorder (GAD\u20107), Neck Disability Index (NDI), and Insomnia Severity Index. Multivariable regression analysis was used to investigate clinical predictors associated with PROMs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 62 MPT patients, the prevalence of clinically relevant dysphagia symptoms (EAT\u201010), elevated symptoms of depression (PHQ\u20108), moderate\/severe symptoms of anxiety (GAD\u20107), moderate\/severe neck pain with activities of daily living (NDI), and moderate\/severe symptoms of insomnia at last follow\u2010up was 32.3%, 15.5%, 7.1%, 17.7%, and 7.2%, respectively. Nonparametric one\u2010sided test revealed that patients treated with adjuvant CRT had significantly worse physical QOL, social\u2010emotional QOL, and swallowing scores than patients treated with surgery alone (<jats:italic>p<\/jats:italic>\u2009=\u20090.01, <jats:italic>p<\/jats:italic>\u2009=\u20090.02, <jats:italic>p<\/jats:italic>\u2009=\u20090.03, respectively); that patients treated with surgery and adjuvant RT had significantly worse physical QOL and social\u2010emotional QOL than patients treated with surgery alone (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01, <jats:italic>p<\/jats:italic>\u2009=\u20090.01, respectively) and that patients treated with surgery and adjuvant CRT had significantly worse swallowing and neck pain than patients treated with surgery and adjuvant RT (<jats:italic>p<\/jats:italic>\u2009=\u20090.03, <jats:italic>p<\/jats:italic>\u2009=\u20090.05, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with surgically treated MPT, adjuvant CRT and RT were associated with worse PROMs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:4549\u20134556, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31554","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T09:46:02Z","timestamp":1717494362000},"page":"4549-4556","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Quality of Life Outcomes for Parotid Malignancies"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7381-9022","authenticated-orcid":false,"given":"Anthony","family":"Tang","sequence":"first","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania 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J.","family":"Contrera","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Pittsburgh  Pittsburgh Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marci L.","family":"Nilsen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Pittsburgh  Pittsburgh Pennsylvania U.S.A."},{"name":"Department of Acute and Tertiary Care University of Pittsburgh School of Nursing  Pittsburgh Pennsylvania 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