{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T04:06:58Z","timestamp":1783138018045,"version":"3.54.6"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to document 10\u2010year outcomes after supracricoid partial laryngectomy (SCPL) in selected cT3M0 laryngeal squamous cell carcinoma (SCC) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This real\u2010life retrospective observational study analyzed an inception cohort of 168 patients with isolated, untreated, selected cT3M0 laryngeal SCC, that were consecutively managed by SCPL during the period 1973\u20132013, and followed up until death or for a minimum of 10\u2009years in 92% of cases at a single French academic and tertiary referral care center. Prior induction chemotherapy, arytenoid cartilage removal, level II\u2013IV neck dissection, and postoperative radiation therapy were performed on 148, 77, 136, and 27 patients, respectively. The main objective was to determine 10\u2010year actuarial local control and laryngeal preservation estimates. Secondary objectives included 10\u2010year actuarial survival and cause\u2010of\u2010death analysis, and assessment of correlations between endpoints and clinical variables. The significance threshold was set at <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.005.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten\u2010year actuarial local control, laryngeal preservation, and survival estimates were 90%, 85%, and 52%, respectively. Salvage treatment resulted in an overall 99% local control rate. Metachronous second primary cancer, intercurrent disease without evidence of SCC, SCPL\u2010related death, and uncontrolled local recurrence accounted for 31%, 26%, 7%, and 2% of causes of death. On univariate analysis, overall local recurrence and laryngeal preservation rates varied significantly, from 5% to 54% and 90% to 46% when resection margins were R0 and R1, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study highlighted successful 10\u2010year outcomes after SCPL, providing further evidence in favor of its integration into the conservative armamentarium for endolaryngeal cT3 SCC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:4557\u20134563, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31568","type":"journal-article","created":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T09:38:38Z","timestamp":1723887518000},"page":"4557-4563","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ten\u2010Year Outcome After Supracricoid Partial Laryngectomy in <scp>cT3M0<\/scp> Laryngeal Squamous Cell Carcinoma\u2014A <scp>STROBE<\/scp> Analysis"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9721-6761","authenticated-orcid":false,"given":"Ollivier","family":"Laccourreye","sequence":"first","affiliation":[{"name":"Service d'Otorhinolaryngologie et de Chirurgie Cervico\u2010Faciale H\u00f4pital Europ\u00e9en Georges Pompidou Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Garcia","sequence":"additional","affiliation":[{"name":"Service d'Otorhinolaryngologie et de Chirurgie Cervico\u2010Faciale H\u00f4pital Europ\u00e9en Georges Pompidou Universit\u00e9 Paris Cit\u00e9  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Christopher","family":"Holsinger","sequence":"additional","affiliation":[{"name":"Division Head &amp; Neck Surgery, Department of Otolaryngology Stanford University  Palo Alto California U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory Steven","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Penn Center for Head &amp; Neck Cancer, Department of Otorhinolaryngology Head &amp; Neck Surgery Pennsylvania University  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"677","article-title":"Technique de la laryngectomie permettant de conserver la perm\u00e9abilit\u00e9 respiratoire: la cricohyoidopexie","volume":"76","author":"Majer H","year":"1959","journal-title":"Ann Oto\u2010Laryng (Paris)"},{"issue":"12","key":"e_1_2_7_3_1","first-page":"681","article-title":"La crico\u2010hyoido\u2010\u00e9piglottopexie. 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