{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T09:10:08Z","timestamp":1750669808712,"version":"3.41.0"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["K24DC019418\u201001"],"award-info":[{"award-number":["K24DC019418\u201001"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Vocal tremor (VT) poses treatment challenges due to uncertain pathophysiology. VT is typically classified into two phenotypes: isolated vocal tremor (iVT) and essential tremor\u2010related voice tremor (ETvt). The impact of phenotypes on upper aerodigestive tract physiology during swallowing remains unclear. Qualitative and quantitative measures were employed to characterize tremor phenotypes and investigate the effects on swallowing physiology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eleven ETvt participants (1 Male, 10 Female; x\u0304 age\u2009=\u200974) and 8 iVT participants (1 Male, 7 Female; x\u0304 age\u2009=\u200971) swallowed 20\u2009mL boluses in cued and uncued conditions under standardized fluoroscopic visualization. Sustained\/a\/productions were captured to assess the rate and extent of fundamental frequency (F0) modulation. Penetration and Aspiration Scale (PAS) scores were obtained and swallowing biomechanics were captured using Swallowtail\u2122 software. Participants also completed the Swallowing Quality of Life (SWAL\u2010QOL) questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hypopharyngeal transit was faster in both VT phenotypes compared with Swallowtail\u2122 normative reference data. Total pharyngeal transit times, however, were only faster in patients with iVT, relative to reference data. No significant differences were observed on the SWAL\u2010QOL or PAS between tremor phenotypes. SWAL\u2010QOL scores revealed that these patients rarely reported dysphagia symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Subtle differences in swallowing patterns were observed across VT phenotypes, possibly related to adaptive mechanisms resulting in quicker pharyngeal bolus transit. Most patients did not report swallowing issues or dysphagia symptoms. This study is foundational for larger studies on this challenging population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4 <jats:italic>Laryngoscope<\/jats:italic>, 134:4599\u20134603, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31581","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T12:18:45Z","timestamp":1720095525000},"page":"4599-4603","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Vocal Tremor on Deglutition: A Pilot Study"],"prefix":"10.1002","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5362-0866","authenticated-orcid":false,"given":"Gary","family":"Gartling","sequence":"first","affiliation":[{"name":"Otolaryngology\u2010Head &amp; Neck Surgery NYU Grossman School of Medicine  New York New York 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U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7577-0267","authenticated-orcid":false,"given":"Aaron","family":"Johnson","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2010Head &amp; Neck Surgery NYU Grossman School of Medicine  New York New York U.S.A."},{"name":"Communicative Sciences and Disorders, Steinhardt School of Culture, Education, and Human Development New York University  New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley","family":"Gherson","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2010Head &amp; Neck Surgery NYU Grossman School of Medicine  New York New York U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Chiappetta","sequence":"additional","affiliation":[{"name":"Otolaryngology\u2010Head &amp; Neck Surgery NYU Grossman School of Medicine  New York New York 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