{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:28Z","timestamp":1786978168651,"version":"build-2736575974"},"reference-count":59,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K23HL127132"],"award-info":[{"award-number":["K23HL127132"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Persistent obstructive sleep apnea (OSA) after adenotonsillectomy (AT) has been reported in 20%\u201330% of children. The aim of this study was to determine the predictive value of drug\u2010induced sleep endoscopy (DISE) at the time of AT on subjective AT outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective cohort study of children aged 2\u201318\u2009years being treated with AT for sleep disordered breathing (SDB) with one or more risk factors for AT failure: age\u2009&gt;7\u2009years, obesity, severe baseline OSA, Black race. All underwent DISE at the time of AT. Potential predictors of subjective AT outcome included age, sex, obesity, and DISE patterns. Multivariable linear regression was used to model predictors of post\u2010AT Pediatric Sleep Questionnaire (PSQ) and OSA\u201018 outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Pre\u2010 and post\u2010AT PSQ\/OSA\u201018 responses were available from 194 children. Mean age was 9.3\u2009\u00b1\u20093.5\u2009years, with 59% obese, 50% female, and 67% White. After AT, mean PSQ score decreased from 0.60\u2009\u00b1\u20090.19 to 0.28\u2009\u00b1\u20090.22,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and mean OSA\u201018 score decreased from 66\u2009\u00b1\u200921 to 37\u2009\u00b1\u200918,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001. The most frequent sites of obstruction were the tonsils (92%), nasal airway (77%), adenoids (64%), and velopharynx (65%). Multivariable regression modeling demonstrated worse outcomes with obesity, male gender, and multilevel obstruction that included the nasal airway and tongue base in addition to adenotonsillar obstruction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Persistent OSA and symptom burden after AT was common in this population. Obesity, male gender, and multilevel obstruction during DISE were all associated with worse subjective outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      3\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 135:377\u2013384, 2025\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.31704","type":"journal-article","created":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T21:59:46Z","timestamp":1724277586000},"page":"377-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Drug\u2010Induced Sleep Endoscopy Predicts Subjective Outcomes of Adenotonsillectomy"],"prefix":"10.1002","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8979-3478","authenticated-orcid":false,"given":"Derek J.","family":"Lam","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"Biostatistics and Design Program Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuan","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Biostatistics and Design Program Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"Quintanilla\u2010Dieck","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace X.","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris A.","family":"Hargunani","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7793-451X","authenticated-orcid":false,"given":"Carol J.","family":"Macarthur","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and Science University  Portland Oregon U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry A.","family":"Milczuk","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Oregon Health and 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