{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:18:56Z","timestamp":1790302736205,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007746","name":"W.K. Kellogg Foundation","doi-asserted-by":"publisher","award":["P\u20106006251\u20102021"],"award-info":[{"award-number":["P\u20106006251\u20102021"]}],"id":[{"id":"10.13039\/100007746","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["1R01MH126531\u201001"],"award-info":[{"award-number":["1R01MH126531\u201001"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["supplement 3R01MH1265 31\u201001S1"],"award-info":[{"award-number":["supplement 3R01MH1265 31\u201001S1"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Given the prevalence of neonatal hearing loss (HL) associated with intrauterine viral exposures, the goal of this study is to provide information on neonatal HL in the context of the COVID\u201019 pandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were drawn from the COVID\u201019 Mother Baby Outcomes (COMBO) Initiative. 1007 participants completed the newborn hearing screen as part of routine clinical care (COMBO\u2010EHR cohort) and 555 completed the National Survey of Children's Health (NSCH) at 2 and\/or 3\u2009years of age for research purposes (COMBO\u2010RSCH cohort). Maternal SARS\u2010CoV\u20102 infection status during pregnancy was determined through electronic health records and maternal\u2010reported questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In adjusted multivariate logistic regression models covarying for newborn age at assessment, mode of delivery, and gestational age at delivery, there was no significant association between intrauterine SARS\u2010CoV\u20102 exposure and newborn hearing screening failure (<jats:italic>OR<\/jats:italic>\u2009=\u20091.05, <jats:italic>95% CI<\/jats:italic>\u2009=\u20090.39\u20132.42, <jats:italic>p\u2009=<\/jats:italic>\u20090.91) in the COMBO\u2010EHR cohort. In the COMBO\u2010RSCH cohort, there were similar non\u2010significant associations between intrauterine exposure to SARS\u2010CoV\u20102 and maternal\u2010reported concern for HL on the NSCH (<jats:italic>OR<\/jats:italic>\u2009=\u20091.19 [95% <jats:italic>CI<\/jats:italic>\u2009=\u20090.30\u20134.24], <jats:italic>p\u2009=<\/jats:italic>\u20090.79).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is no association between intrauterine exposure to SARS\u2010CoV\u20102 and failed hearing screen in neonates. Similarly, based on the NSCH, there is no association between intrauterine exposure to SARS\u2010CoV\u20102 and maternal\u2010reported concern for hearing in toddlers. These results offer reassurance given the widespread nature of this pandemic with tens of millions of fetuses having a history of intrauterine exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>Level 4 <jats:italic>Laryngoscope<\/jats:italic>, 2024<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31739","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T12:25:31Z","timestamp":1725452731000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Risk of Hearing Loss in Neonates and Toddlers with in Utero Exposure to <scp>SARS<\/scp>\u2010<scp>CoV<\/scp>\u20102"],"prefix":"10.1002","author":[{"given":"Imaal","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3131-5510","authenticated-orcid":false,"given":"Michelle","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head &amp; Neck Surgery Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitoria","family":"Chaves","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiyang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9ane","family":"Lavall\u00e9e","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Warmingham","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Firestein","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret H.","family":"Kyle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaylee","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma T.","family":"Merriman","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3695-9024","authenticated-orcid":false,"given":"Westin","family":"Mace","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dani","family":"Dumitriu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Columbia University Irving Medical Center  New York NY USA"},{"name":"Department of Psychiatry Columbia University Irving Medical Center  New York NY USA"},{"name":"NewYork\u2010Presbyterian  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Lalwani","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Columbia University Irving Medical Center  New York NY USA"},{"name":"NewYork\u2010Presbyterian  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,4]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"OchaniRK AsadA YasminF et al.COVID\u201019 Pandemic: From Origins to Outcomes. 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