{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T23:02:15Z","timestamp":1783551735793,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T00:00:00Z","timestamp":1725321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"abstract":"<jats:p>Pembrolizumab is a monoclonal antibody with increasing use in many malignancies. We describe a case of pembrolizumab\u2010associated bullous pemphigoid (BP) with laryngeal involvement in a 69\u2010year\u2010old male patient. Diagnosis was made after 2\u2009months of symptoms via biopsy of concurrent, easily accessible cutaneous lesions. Pembrolizumab was discontinued and the patient was started on steroids and dupilumab with ultimate resolution of his cutaneous and laryngeal lesions while on immunosuppression. This case report describes the third case of pembrolizumab\u2010associated laryngeal pemphigoid to increase awareness of this rare immune\u2010related adverse effect. <jats:italic>Laryngoscope<\/jats:italic>, 2024<\/jats:p>","DOI":"10.1002\/lary.31743","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T10:25:47Z","timestamp":1725359147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Pembrolizumab\u2010Associated Bullous Pemphigoid with Laryngeal Involvement"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6112-8361","authenticated-orcid":false,"given":"Vasiliki","family":"Triantafillou","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery University of Pennsylvania, Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Leahy","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery University of Pennsylvania, Perelman School of Medicine  Philadelphia Pennsylvania U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/FONC.2023.1095694"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JVOICE.2022.12.028"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0000000000000280"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17395"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2021.01.012"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.31743","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T10:25:49Z","timestamp":1725359149000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.31743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":5,"alternative-id":["10.1002\/lary.31743"],"URL":"https:\/\/doi.org\/10.1002\/lary.31743","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,3]]},"assertion":[{"value":"2024-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"lary.31743"}}