{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:04:59Z","timestamp":1791986699244,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271135"],"award-info":[{"award-number":["82271135"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["82000950"],"award-info":[{"award-number":["82000950"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Eosinophilic chronic rhinosinusitis with nasal polyps (eos\u2010CRSwNP), especially those with diffuse disease as indicated by CT scans, has high recurrence rate and low control rate after endoscopic sinus surgery (ESS). Most of them are difficult to treat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study sought to identify if eos\u2010CRSwNP patients were to undergo surgery earlier, while the disease is still limited on CT, they might achieve better postoperative outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study enrolled eos\u2010CRSwNP patients with different degree of sinus involvement who underwent primary ESS and compared the surgical outcomes of the patients exhibiting mild sinus involvement with those displaying severe sinus involvement. The demographic data, preoperative disease severity, and surgery outcomes at 1\u2009year postoperatively were collected. CRS control status was the primary endpoint to evaluate the outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 118 patients with at least one\u2010year follow\u2010up. The overall uncontrolled rate was 33.1% at 1\u2009year postoperatively. The best cut\u2010off value for CT Lund\u2013Mackay (L\u2010M) score was 13 to predict the uncontrolled status (AUC\u2009=\u20090.67). Then, patients were divided into the mild group (L\u2010M\u2009&lt;\u200913, <jats:italic>n<\/jats:italic>\u2009=\u200970) and the severe group (L\u2010M\u2009\u2265\u200913, <jats:italic>n<\/jats:italic>\u2009=\u200948) according to L\u2010M score. The follow\u2010up data indicated that 24.3% of patients (17\/70) in the mild group and 45.8% of patients (22\/48) in the severe group were uncontrolled (<jats:italic>p<\/jats:italic>\u2009=\u20090.015). Postoperative endoscopic score in the mild group was significantly better than those in the severe group (<jats:italic>p<\/jats:italic>\u2009=\u20090.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ESS performed on eos\u2010CRSwNP patients with mild sinus involvement have better postoperative outcomes at 1\u2009year than patients with severe sinus involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3 <jats:italic>Laryngoscope<\/jats:italic>, 135:1021\u20131028, 2025<\/jats:p><\/jats:sec>","DOI":"10.1002\/lary.31846","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T11:55:38Z","timestamp":1728993338000},"page":"1021-1028","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Impact of Sinus <scp>CT<\/scp> Severity Score on the Outcomes of Endoscopic Sinus Surgery in Eosinophilic 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