{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:31:30Z","timestamp":1747150290195,"version":"3.40.5"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Autoimmune inner ear disease (AIED) is an uncommon cause of fluctuating sensorineural hearing loss (SNHL), which is diagnosed by exclusion and required a high index of suspicion. Secondary AIED, which accompanies other autoimmune diseases, occurs in up to 30% of AIED cases. Secondary AIED is a rare manifestation of paraneoplastic syndrome, and the causal malignancy may be occult initially. Detecting and treating associated diseases, along with the use of immunosuppressants, are the mainstay for the management of AIED.<\/jats:p><jats:p>Herein, we presented a woman with bilateral fluctuating and progressive SNHL, partially responding to steroid or immunosuppressant treatment. Her hearing eventually stabilized after completing the treatment for diffuse large B cell lymphoma, which was diagnosed 6 months after the onset of hearing loss. This case serves as a reminder to physicians to be aware of AIED in cases of fluctuating SNHL and the possibility of associated malignancy alongside autoimmune disturbance. <jats:italic>Laryngoscope<\/jats:italic>, 135:1496\u20131498, 2025<\/jats:p>","DOI":"10.1002\/lary.31870","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T09:31:58Z","timestamp":1729675918000},"page":"1496-1498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bilateral Fluctuating Sensorineural Hearing Loss as a Paraneoplastic Manifestation for Lymphoma"],"prefix":"10.1002","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5145-0743","authenticated-orcid":false,"given":"Ting\u2010Chia","family":"Young","sequence":"first","affiliation":[{"name":"Department of Medicine Mackay Medical College  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010Hsiu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medicine Mackay Medical College  New Taipei City Taiwan"},{"name":"Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine Mackay Memorial Hospital  Taipei City Taiwan"},{"name":"Mackay Junior College of Medicine, Nursing, and Management  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9014-8986","authenticated-orcid":false,"given":"Chia\u2010Huei","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery MacKay Memorial Hospital  Taipei Taiwan"},{"name":"Department of Audiology and Speech\u2010Language Pathology Mackay Medical College  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8698-4212","authenticated-orcid":false,"given":"Hung\u2010Ching","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery MacKay Memorial Hospital  Taipei Taiwan"},{"name":"Department of Audiology and Speech\u2010Language Pathology Mackay Medical College  New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4711-7818","authenticated-orcid":false,"given":"Pey\u2010Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery MacKay Memorial Hospital  Taipei Taiwan"},{"name":"Department of Audiology and Speech\u2010Language Pathology Mackay Medical College  New Taipei City Taiwan"},{"name":"Department of Otolaryngology National Taiwan University Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket009"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/mao.0000000000000663"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39859"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2058738418808680"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0099"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000014470"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.31870","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T04:24:18Z","timestamp":1741839858000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.31870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,23]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/lary.31870"],"URL":"https:\/\/doi.org\/10.1002\/lary.31870","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"type":"print","value":"0023-852X"},{"type":"electronic","value":"1531-4995"}],"subject":[],"published":{"date-parts":[[2024,10,23]]},"assertion":[{"value":"2024-05-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}