{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:58:31Z","timestamp":1787065111586,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the diagnostic accuracy of 18F\u2010FDG\u2010PET\/CT compared to conventional imaging modalities (CIM) to detect recurrence of primary salivary gland cancers (SGCs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>Review performed on December 26, 2024, using Embase, CINHAL, MEDLINE, and PubMed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>Two blinded reviewers selected studies reporting diagnostic accuracy of PET\/CT in identifying locoregional recurrence and\/or metastasis in patients with SGCs. The analysis was performed adhering to PRISMA guidelines using R 4.3.3. Pooled analysis with 95% confidence intervals (CI) were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 12 studies were retained from the systematic review, including 264 patients evaluated in the meta\u2010analysis. For local recurrence, there was a pooled sensitivity of 0.86 (95% CI 0.73\u20130.93) and a pooled specificity of 0.95 (95% CI 0.92\u20130.97) for PET\/CT, and a pooled sensitivity of 0.89 (95% CI 0.80\u20130.94) and a pooled specificity of 0.91 (95% CI 0.79\u20130.97) for CIM (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.90). For regional metastasis, there was a pooled sensitivity of 0.90 (95% CI 0.73\u20130.97) and a pooled specificity of 0.96 (95% CI 0.92\u20130.98) for PET\/CT, and a pooled sensitivity of 0.80 (95% CI 0.62\u20130.91) and a pooled specificity of 0.95 (0.90\u20130.98) for CIM (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.26). For distant metastasis, there was a pooled sensitivity of 0.96 (95% CI 0.90\u20130.99) and a pooled specificity of 0.95 (95% CI 0.85\u20130.98) for PET\/CT, and a pooled sensitivity of 0.80 (95% CI 0.71\u20130.86) and a pooled specificity of 0.97 (95% CI 0.87\u20130.99) for CIM (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>18F\u2010FDG\u2010PET\/CT imaging is accurate for the detection of SGC recurrence, particularly for the detection of regional and distant metastases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>\n                      NA\n                      <jats:italic>Laryngoscope<\/jats:italic>\n                      , 135:1884\u20131898, 2025\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.32003","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T06:32:45Z","timestamp":1737009165000},"page":"1884-1898","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>18F<\/scp>\n                    \u2010\n                    <scp>FDG PET<\/scp>\n                    \/\n                    <scp>CT<\/scp>\n                    for Surveillance in Salivary Gland Cancers: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7362-2633","authenticated-orcid":false,"given":"Emily","family":"Ajit\u2010Roger","sequence":"first","affiliation":[{"name":"Faculty of Medicine McGill University  Montreal Quebec 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