{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T13:12:53Z","timestamp":1784293973230,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prevalence of periodic limb movements (PLMS) in children with obstructive sleep apnea (OSA) and assess the effect of adenotonsillectomy (AT) on PLMS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Charts of children with OSA who underwent AT were reviewed for demographics, obstructive apnea\u2010hypopnea index, and PLMS before and after AT. Prevalence of elevated periodic limb movement index (PLMI), defined as PLMS &gt;\u20095 events\/h, was compared with \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      test or Fisher's exact. Paired\n                      <jats:italic>t<\/jats:italic>\n                      \u2010test and Wilcoxon signed rank test were used to compare PLMI pre\u2010and post\u2010AT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Elevated PLMI occurred in 114 (9.8%) of 1159 children (676 male,483 female, median age\u2009=\u20095). The prevalence of elevated PLMI was similar in gender, ethnicity, race, and weight categories. Compared to toddlers, the odds of elevated PLMI increased 22.1 times in preschoolers (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.001), 35.4 times in grade\u2010schoolers (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.001), and 30.8 times in teenagers (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.001). Compared to children with mild OSA, the odds of elevated PLMI increased 2.3 times in children with moderate OSA (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) and 1.9 times in those with severe OSA (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). Of the 54 children who had a polysomnogram after AT, 46 (85%) resolved and 8 (15%) had persistent elevated PLMI. PLMI after AT decreased from 11.9\u2009\u00b1\u20097.6 to 2.9\u2009\u00b1\u20096.5 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Elevated PLMI is common in children with OSA undergoing AT. PLMI resolves after AT in most children with OSA.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Level of Evidence:<\/jats:bold>\n                      4.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.32314","type":"journal-article","created":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T08:38:56Z","timestamp":1749285536000},"page":"4428-4432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Periodic Limb Movements Before and After Adenotonsillectomy in Children With Obstructive Sleep Apnea"],"prefix":"10.1002","volume":"135","author":[{"given":"Amor","family":"Niksic","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0503-7051","authenticated-orcid":false,"given":"Seckin O.","family":"Ulualp","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Division of Pediatric Otolaryngology, Children's Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Claire","family":"Chapel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7871-4060","authenticated-orcid":false,"given":"Christopher","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Division of Pediatric Otolaryngology, Children's Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicity","family":"Lenes\u2010Voit","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Division of Pediatric Otolaryngology, Children's Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7890-0541","authenticated-orcid":false,"given":"Ron B.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Division of Pediatric Otolaryngology, Children's Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2008.12.002"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.08.778"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2869.2003.00332.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.1458"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-054X.2001.01166.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.1460"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3928"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/26.6.735"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.05.004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2024.00034"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2023.10.033"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2020.06.004"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.11390"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/27.2.313"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1671"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.32314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.32314","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.32314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T15:01:49Z","timestamp":1771081309000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.32314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,7]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/lary.32314"],"URL":"https:\/\/doi.org\/10.1002\/lary.32314","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,7]]},"assertion":[{"value":"2025-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}