{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:19:03Z","timestamp":1790011143186,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Patient frailty negatively impacts postsurgical outcomes across multiple specialties. Commonly used frailty scoring systems include the Modified 5\u2010Item Frailty Index (MFI\u20105) and the Clinical Risk Analysis Index (RAI\u2010C). We compared these frailty indices in predicting postsurgical outcomes in otolaryngology, a comparison that has never been completed to date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective chart review of patients undergoing otolaryngologic surgery at a quaternary care medical center (2022\u20132024) with an RAI\u2010C score available for analysis. Chi\u2010square analysis and ROC curves were utilized to determine associations and predictive ability of each scoring system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1209 patients, 21% met MFI\u20105 frailty criteria (MFI\u20105 score &gt;\u20091), and 23% met RAI\u2010C frailty criteria (RAI\u2010C score\u2009&gt;\u200930). The Pearson correlation coefficient between MFI\u20105 and RAI\u2010C was 0.481 (95% CI [0.43, 0.53]), indicating a moderate correlation between the two metrics. Patients deemed frail by RAI\u2010C had 5.7 times higher odds of experiencing a postoperative complication than non\u2010frail counterparts (95% CI [3.51, 9.28],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), but MFI\u20105 frailty status was not associated with postoperative complications. Both RAI\u2010C and MFI\u20105 demonstrated significant predictive ability for 30\u2010day readmission (AUC 0.77, 95% CI [0.64, 0.89] vs. AUC 0.76, 95% CI [0.61, 0.88]), respectively. When compared to MFI\u20105, RAI\u2010C had greater predictive performance for all other postoperative outcomes in this study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>RAI\u2010C outperformed MFI\u20105 in predicting postoperative outcomes in patients undergoing otolaryngologic surgeries. RAI\u2010C assessment should be considered in frailty research, multidisciplinary treatment planning, and managing patient expectations and outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.32408","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T10:23:11Z","timestamp":1754043791000},"page":"4655-4663","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Risk Analysis Index Versus Modified Frailty Index: Outcomes After Otolaryngologic Surgery"],"prefix":"10.1002","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9860-5248","authenticated-orcid":false,"given":"Lauran K.","family":"Evans","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine at University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Tamamian","sequence":"additional","affiliation":[{"name":"San Diego School of Medicine University of California  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiree","family":"Delavary","sequence":"additional","affiliation":[{"name":"A.T. Still University School of Osteopathic Medicine  Mesa Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9914-9670","authenticated-orcid":false,"given":"Matthew E.","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine at University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2032-3141","authenticated-orcid":false,"given":"Hong\u2010Ho","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Stanford University  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7068-9534","authenticated-orcid":false,"given":"Maie","family":"St. John","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine at University of California Los Angeles  Los Angeles California USA"},{"name":"UCLA Head and Neck Cancer Program  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh K.","family":"Chhetri","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery David Geffen School of Medicine at University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(19)31786\u20106"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933\u2010019\u20100885\u20102"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.m146"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13321"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28307"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.24588"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2016.4202"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/2023.2.SPINE221019"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.899"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wnsx.2023.100203"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2021.09.026"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998211010443"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2017.11.005"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463\u2010022\u201000607\u20104"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2017.0412"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.12.168"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1227\/neuprac.0000000000000044"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2024.09.089"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.14245\/ns.2346496.248"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.14245\/ns.2244326.163"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000004389"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813519749"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.32408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T09:06:12Z","timestamp":1765875972000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.32408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/lary.32408"],"URL":"https:\/\/doi.org\/10.1002\/lary.32408","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2024-12-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}