{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:40:58Z","timestamp":1772890858268,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To describe the demographics, clinical presentation, treatment, and complications of piercing\u2010induced auricular perichondritis (P\u2010\n                      <jats:styled-content style=\"fixed-case\">IAP<\/jats:styled-content>\n                      ) and non\u2010\n                      <jats:styled-content style=\"fixed-case\">PIAP.<\/jats:styled-content>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We reviewed the medical records of consecutive patients diagnosed and treated for P\u2010\n                      <jats:styled-content style=\"fixed-case\">IAP<\/jats:styled-content>\n                      and P\u2010\n                      <jats:styled-content style=\"fixed-case\">FAP<\/jats:styled-content>\n                      between 2006 and 2021. The retrieved data included demographics, comorbidities, etiology, location, treatment, complications, and outcome, and they were compared between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 217 patients fulfilled the inclusion criteria. Of them, 120 (55.3%) comprised the P\u2010\n                      <jats:styled-content style=\"fixed-case\">IAP<\/jats:styled-content>\n                      group, which was characterized by significantly younger age and fewer comorbidities. The 97 non\u2010\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      patients tended to present with more systemic and regional signs, while the\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      group presented with localized signs and significantly more abscess formation and significantly more colonization with\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      <\/jats:styled-content>\n                      . Time from causative event to symptom onset was significantly shorter in the\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      group (18.9\u2009\u00b1\u200938.7\u2009days) compared to the non\u2010\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      group (29.8\u2009\u00b1\u200962.9\u2009days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.021), which also had longer hospitalization. Complications included drainage or debridement, recurrent disease, &gt;\u200921\u2009days of antibiotic treatment, or requirement of a central line. Abscess formation was the most significant variable associated with complications (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      35.75 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 13.12\u201397.35,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001] for the entire cohort,\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      35.59 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 10.84\u2013116.84,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001] for the\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      group, and\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      47.30 [95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 5.33\u2013419.67,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001] for the non\u2010\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      group). No other variables reached a level of significance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      has different demographics, comorbidities, disease course, and microbiology compared to non\u2010\n                      <jats:styled-content style=\"fixed-case\">PIAP<\/jats:styled-content>\n                      . Abscess formation is an independent factor for complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>3.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.32409","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T12:15:40Z","timestamp":1752063340000},"page":"4693-4702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Auricular Perichondritis in the Cartilage Piercing Era"],"prefix":"10.1002","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5904-1291","authenticated-orcid":false,"given":"Omer J.","family":"Ungar","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noa","family":"Bursztyn","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6474-7435","authenticated-orcid":false,"given":"Shahaf","family":"Shilo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6905-3034","authenticated-orcid":false,"given":"Ophir","family":"Handzel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery University of Rochester  Rochester New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidal","family":"Muhanna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2356-9147","authenticated-orcid":false,"given":"Yahav","family":"Oron","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rani","family":"Abu Eta","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narin N.","family":"Carmel Neiderman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, affiliated to Grey School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.8.981"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2005.06.003"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197605000-00006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215107005877"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198103000-00013"},{"issue":"1","key":"e_1_2_9_7_1","first-page":"58","article-title":"The Incidences of Chondritis and Perichondritis Associated With the Surgical Manipulation of Auricular Cartilage","volume":"30","author":"Kaplan A. 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