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The embryology and pathology of first cleft anomalies are discussed and an approach to the diagnosis and management of these lesions is given. In addition, a patient with a branchial cleft defect involving the middle ear space is reported.<\/jats:p>","DOI":"10.1002\/lary.5540900309","type":"journal-article","created":{"date-parts":[[2009,10,20]],"date-time":"2009-10-20T19:53:30Z","timestamp":1256068410000},"page":"423-436","source":"Crossref","is-referenced-by-count":159,"title":["First branchial cleft anomalies"],"prefix":"10.1002","volume":"90","author":[{"given":"Kerry D.","family":"Olsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas E.","family":"Maragos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis H.","family":"Weiland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,10,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800114112"},{"key":"e_1_2_1_3_2","volume-title":"Developmental Anatomy: A Textbook and Laboratory Manual of Embryology","author":"Arey L. 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