{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:51:36Z","timestamp":1786978296446,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008376","name":"Helsingin ja Uudenmaan Sairaanhoitopiiri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Patient perspectives have become an important aspect of healthcare evaluation. To measure health related quality of life (HRQoL), it is essential to apply well\u2010researched HRQoL instruments. Current instruments for chronic sialadenitis have limitations and, thus, we created a new disease\u2010specific HRQoL tailored for chronic sialadenitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      COSMIN guidelines were followed. Initially, a preliminary 24\u2010item questionnaire was created. Untreated patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009126) were recruited to complete the preliminary questionnaire alongside the generic HRQoL instrument, 15D. ENT specialists evaluated the severity of the disease and the disability caused by the disease. Additionally, a control group of healthy adults was recruited for comparison. Based on patients' responses, items were reduced using predefined criteria, and the final instrument was validated with statistical analyses. Cronbach's\n                      <jats:italic>\u03b1<\/jats:italic>\n                      was used to measure internal consistency, and the intraclass correlation coefficient (ICC) was used to measure test\u2013retest reliability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The most suitable recall period was 3\u2009months. With statistical analyses, the number of items was reduced to 14, leading to the creation of the final instrument, the Chronic Sialadenitis Outcome Test 14, CSOT\u201014. CSOT\u201014 had good internal consistency (Cronbach's\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u2009=\u20090.871) and test\u2013retest reliability (ICC\u2009=\u20090.911), and it differentiated patients from healthy controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A novel instrument for chronic sialadenitis, CSOT\u201014, that clearly differentiated patients from healthy controls was created and validated. The instrument can be used in daily clinical practice for patients with chronic sialadenitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>2.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70003","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T11:05:47Z","timestamp":1754046347000},"page":"158-167","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Development of the Chronic Sialadenitis Outcome Test\u201014 for Chronic Sialadenitis"],"prefix":"10.1002","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0649-057X","authenticated-orcid":false,"given":"Juha","family":"Vartiainen","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, P\u00e4ij\u00e4t\u2010H\u00e4me Central Hospital  Lahti Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Kuopio University Hospital and University of Kuopio  Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta","family":"Saarinen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha","family":"Laakso","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Jokela","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Hospital Nova of Central Finland  Jyv\u00e4skyl\u00e4 Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Haaramo","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3097-1118","authenticated-orcid":false,"given":"Aaro","family":"Haapaniemi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aarno","family":"Dietz","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery Kuopio University Hospital and University of Kuopio  Kuopio Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saku T.","family":"Sinkkonen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2014Head and Neck Surgery, Head and Neck Center Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,1]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f167"},{"issue":"11","key":"e_1_2_8_3_1","first-page":"882","article-title":"Salivary Gland Disorders","volume":"89","author":"Wilson K. 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