{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:08:20Z","timestamp":1787170100939,"version":"build-2736575974"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report a rare case of a sterile nasal septal abscess (NSA) occurring as an extraintestinal manifestation of ulcerative colitis (UC), accompanied by a novel histopathologic finding. A 40\u2010year\u2010old woman with relapsed UC presented with nasal swelling, purulent discharge, hematochezia, and skin lesions. Computed tomography revealed an anterior NSA, and emergent endoscopic drainage was performed. Despite broad\u2010spectrum antibiotics, her condition worsened, and corticosteroids were initiated. Histopathologic analysis of the nasal mucosa demonstrated crypt abscess\u2010like neutrophilic infiltration within glandular structures, resembling colonic crypt abscesses in active UC. Cultures were negative, and her condition improved with immunosuppressive therapy. To our knowledge, this is the first reported case of a sterile NSA with crypt abscess\u2010like structures in the nasal mucosa, expanding the histopathologic spectrum of sinonasal manifestations in UC. Early recognition and prompt immunosuppressive therapy are essential to avoid complications such as saddle nose deformity.<\/jats:p>","DOI":"10.1002\/lary.70106","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T10:11:14Z","timestamp":1756894274000},"page":"678-682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sterile Nasal Septal Abscess in Ulcerative Colitis With Crypt Abscess\u2010Like Neutrophilic Infiltration"],"prefix":"10.1002","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6871-1108","authenticated-orcid":false,"given":"Masakazu","family":"Murayama","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, School of Medicine Showa Medical University  Tokyo Japan"},{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery Odawara Municipal Hospital  Odawara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihito","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery Odawara Municipal Hospital  Odawara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Yokose","sequence":"additional","affiliation":[{"name":"Department of Pathology Odawara Municipal Hospital  Odawara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshikazu","family":"Shimane","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, School of Medicine Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"issue":"2","key":"e_1_2_7_2_1","first-page":"26","article-title":"Pyoderma Gangrenosum With Spleen Involvement. Review of the Literature and Case Report","volume":"10","author":"Cosgarea R.","year":"2016","journal-title":"Journal of Dermatology Case Reports"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2020.04.019"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000543761"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-012-8349-4"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00966-2"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.70106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:50:46Z","timestamp":1768207846000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.70106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,3]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/lary.70106"],"URL":"https:\/\/doi.org\/10.1002\/lary.70106","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,3]]},"assertion":[{"value":"2025-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}