{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T18:21:05Z","timestamp":1768242065615,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007710","name":"University of Connecticut","doi-asserted-by":"publisher","award":["Clinical Research and Innovation Seed Program"],"award-info":[{"award-number":["Clinical Research and Innovation Seed Program"]}],"id":[{"id":"10.13039\/100007710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The development of an endotracheal tube (ETT) prototype to measure the pressure on the posterior glottis during intubation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Three\n                      <jats:styled-content style=\"fixed-case\">ETTs<\/jats:styled-content>\n                      , size 6, 7, and 8\u2009mm, were modified with a piezoelectric pressure sensor. These ETTs were then used to intubate a laryngeal model. Pressures were measured at a hypopharyngeal laryngeal angle (\n                      <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\n                      ) of 90\u00b0, and the laryngeal platform was raised to create a more acute\n                      <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\n                      ranging from 90\u00b0 to 45\u00b0. These same ETTs were also used to intubate the larynx of a fresh frozen cadaver, with pressure measured with the head in neutral and flexed positions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The pressures exerted by the 6\u2009mm\n                      <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content>\n                      ranged from 7.33\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      at 90 degrees\n                      <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\n                      to 62.57\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      at 45 degrees\n                      <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\n                      . The 7\u2009mm\n                      <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content>\n                      ranged from 5.42 to 451.19\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      and the 8\u2009mm\n                      <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content>\n                      pressure ranged from 136.98 to 534.38\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      , respectively. The differences were statistically significant. The cadaveric study revealed the average pressure for the 6\u2010, 7\u2010, and 8\u2010mm\n                      <jats:styled-content style=\"fixed-case\">ETT<\/jats:styled-content>\n                      to be 2.03, 166.78, and 228.49\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      , respectively, in the neutral position and 0.85, 30.37, and 158.51\u2009cm\n                      <jats:styled-content style=\"fixed-case\">\n                        H\n                        <jats:sub>2<\/jats:sub>\n                        O\n                      <\/jats:styled-content>\n                      , respectively, in the flexed position. These differences were statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Posterior laryngeal pressure monitoring can be conducted utilizing ETT\u2010based pressure sensors. Progression of this technology may help minimize laryngeal injury caused by intubation by determining which patients may be optimal candidates for early tracheostomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>5<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70113","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T15:39:03Z","timestamp":1757000343000},"page":"865-871","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of a Novel Endotracheal Tube to Measure Posterior Laryngeal Pressure"],"prefix":"10.1002","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4021-7576","authenticated-orcid":false,"given":"Denis","family":"Lafreniere","sequence":"first","affiliation":[{"name":"Division of Otolaryngology UConn Health  Farmington Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amelia","family":"Geist","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology UConn Health  Farmington Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2014.10.012"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.11.004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003368"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948309200506"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29192"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489415608867"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198403000-00010"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2659-x"},{"issue":"5","key":"e_1_2_9_10_1","first-page":"511","article-title":"Histopathology of Endotracheal Intubation. An Autopsy Study of 99 Cases","volume":"88","author":"Donnelly W. H.","year":"1969","journal-title":"Archives of Pathology"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988008800625"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941112000201"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31138"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeq239"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.1118"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198203000-00009"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28952"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4838-7"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-1138-8"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02439735"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1984.tb08932.x"},{"key":"e_1_2_9_22_1","first-page":"S1","article-title":"Electrophhysiologic Recurrent Laryngeal Nerve Monitoring During Thyroid an Dparathyroid Surgery: International Standards Guideline Statement","volume":"121","author":"Randolf G. W.","year":"2011","journal-title":"Laryngoscope"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27237"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.70113","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T08:50:21Z","timestamp":1768207821000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.70113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,4]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/lary.70113"],"URL":"https:\/\/doi.org\/10.1002\/lary.70113","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,4]]},"assertion":[{"value":"2025-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}