{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:48:13Z","timestamp":1789649293214,"version":"4.0.0"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T00:00:00Z","timestamp":1757721600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Studies have shown balloon dilation of the Eustachian tube (BDET) to play a beneficial role in the treatment of obstructive Eustachian tube (ET) dysfunction in adults. This analysis was undertaken to clarify this role.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data Sources<\/jats:title>\n                    <jats:p>\n                      Cochrane Central Register of Controlled Trials, PubMed, Embase Ovid,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      , WHO\u2010ICTRP, EU Clinical Trials Register, and Google Scholar.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review Methods<\/jats:title>\n                    <jats:p>This review analyzed randomized controlled trials published through 29 February 2024, updated on 11 January 2025, comparing the effects of BDET with no treatment, medical treatment, or auto\u2010inflation exercises. Outcomes included improvement in tympanogram, decrease in air\u2010bone gap on audiometry, new ability to perform Valsalva, otoscopic confirmation of improvement in tympanic membrane retraction, or new documented mobility of the membrane on pneumatic otoscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven trials were analyzed, four excluded with reasons and seven included in the analysis. On analysis of 315 participants from three trials who underwent BDET in comparison to control, the relative risk of benefit of post\u2010operatively reaching Type A tympanogram was 4.68 (2.88\u20137.51) in comparison to control. BDET was also seen to offer significantly more closure in air\u2010bone gap when performed along with tympanoplasty in patients with adhesive otitis media at both 3\u2010month (air\u2010bone gap closure of 3.82\u2009dB [0.47\u20137.17\u2009dB]) and 6\u2010month (air\u2010bone gap closure of 4.06\u2009dB [1.78\u20136.34\u2009dB]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In adults with chronic ET dysfunction, BDET increased the chance of achieving a Type A tympanogram curve and significantly improved air\u2010bone gap closure when performed along with cartilage tympanoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>1a.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70131","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T10:50:16Z","timestamp":1757760616000},"page":"1077-1087","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Balloon Dilation of the Eustachian Tube for Adults With Chronic Obstructive Eustachian Tube Dysfunction: A Meta\u2010Analysis"],"prefix":"10.1002","volume":"136","author":[{"given":"Poonam","family":"Raj","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Armed Forces Medical College  Pune Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6589-3108","authenticated-orcid":false,"given":"Tulasi Kota","family":"Karanth","sequence":"additional","affiliation":[{"name":"Department of ENT\u2010HNS Military Hospital Prayagraj  Prayagraj Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8641-7370","authenticated-orcid":false,"given":"Dennis","family":"Poe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Communication Enhancement Boston Children's Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1944.00680010374001"},{"issue":"5","key":"e_1_2_8_3_1","article-title":"A Study of the Anatomy of the Eustachian Tube for Its Surgical Approach in Otorhinolaryngology","volume":"15","author":"Yasmin N.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_8_4_1","volume-title":"Diagnosis and Tests of Function. 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