{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:13:33Z","timestamp":1789020813621,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008626","name":"Cochlear","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008626","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the long\u2010term audiometric and speech perception outcomes in Hybrid cochlear implant recipients meeting hybrid or electric\u2010acoustic stimulation (EAS) indications, and to identify factors, including age, sex, and duration of hearing loss, that may contribute to outcome variability. Additionally, the study evaluates the impact of EAS on speech perception.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from two clinical trials and retrospective data from the University of Iowa were combined for a total dataset of 150 Cochlear Nucleus Hybrid L24 (Cochlear Ltd., Sydney, Australia) cochlear implant recipients. Audiometric outcomes, as quantified by low\u2010frequency pure\u2010tone average (LFPTA; 125\u2013500\u2009Hz), and speech perception outcomes, including unilateral and bilateral CNC words in quiet and AzBio +5\u2009dB SNR sentences in noise, were assessed preoperatively and postoperatively up to 5\u2009years postactivation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Functional low\u2010frequency acoustic hearing (LFPTA &lt;\u200980\u2009dB HL) was preserved in 72.9% of Hybrid L24 recipients up to 5\u2009years postactivation, with audiometric changes stabilizing around 1\u2009year. Significant improvements were observed in speech perception both in quiet and in noise. Age at implantation was a significant predictor of both audiometric and speech outcomes, with younger recipients demonstrating greater speech\u2010in\u2010noise improvements and a greater likelihood of maintaining functionally aidable hearing. EAS users demonstrated superior speech outcomes compared to electric\u2010only users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cochlear implantation for EAS candidates provides long\u2010term preservation of acoustic hearing and improved speech perception outcomes, particularly in younger recipients. These findings support the use of hybrid\/EAS cochlear implantation in candidates with low\u2010frequency hearing and highlight the benefit of EAS in enhancing speech understanding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>3<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      Relevant studies were registered on\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                      under trial registration numbers NCT00678899 (pivotal study group), NCT02379273 (continuation of pivotal study group), and NCT02379819 (post\u2010approval study group)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70195","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T20:55:03Z","timestamp":1759956903000},"page":"1475-1486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors Affecting Audiometric and Speech Perception Outcomes in Hybrid Cochlear Implant Recipients"],"prefix":"10.1002","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4473-1214","authenticated-orcid":false,"given":"Paul N.","family":"Reinhart","sequence":"first","affiliation":[{"name":"Cochlear Americas  Lone Tree Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron J.","family":"Parkinson","sequence":"additional","affiliation":[{"name":"Cochlear Americas  Lone Tree Colorado 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