{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:18:28Z","timestamp":1791976708892,"version":"4.4.0"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n \n Voice recovery in unilateral vocal fold paralysis (\n UVFP<\/jats:styled-content>\n ) has been shown to follow a two\u2010phase time course, with an \u201cearly\u201d group consistent with low\u2010grade neuronal injuries and a \u201clate\u201d group with more severe injuries. The aims of this study were to (1) determine if\n VF<\/jats:styled-content>\n motion recovery also follows a two\u2010phase model, and (2) determine if early motion recovery portends a higher likelihood of greater return of motion.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n UVFP<\/jats:styled-content>\n patients over a 16\u2010year period were included in this retrospective study. Laryngoscopies from each visit were reviewed to determine the degree of motion recovery. Time from the onset of paralysis to motion or voice recovery was collected. The time to recovery data were fit to a previously described two\u2010phase model incorporating an exponentially modified Gaussian. Time courses of voice and various degrees of motion recovery were compared using Kaplan\u2013Meier estimates.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n 23.7% (213\/899) patients recovered some degree of VF motion, with 16.8% (156\/931) experiencing spontaneous voice recovery. VF motion recovery followed a two\u2010phase model for peripheral, non\u2010idiopathic etiologies. Trace motion occurs approximately 1\u2009month following voice recovery, with further motion occurring 2\u2009months following voice recovery. Patients who recovered VF motion early in their clinical course (<\u2009120\u2009days) were more likely to develop greater degrees of motion recovery (\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Return of\n VF<\/jats:styled-content>\n motion appears to be possible in some cases with higher grade neuronal injuries. Recovery of voice, return of trace\n VF<\/jats:styled-content>\n motion, and return of greater degrees of motion appear to be temporally sequenced.\n <\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n 3<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lary.70308","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T05:53:53Z","timestamp":1765605233000},"page":"2212-2219","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Natural History of Vocal Fold Motion Recovery in Unilateral Vocal Fold Paralysis"],"prefix":"10.1002","volume":"136","author":[{"given":"Rishi","family":"Suresh","sequence":"first","affiliation":[{"name":"Clinical Center for Voice Care, Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2594-0731","authenticated-orcid":false,"given":"Lesley F.","family":"Childs","sequence":"additional","affiliation":[{"name":"Clinical Center for Voice Care, Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1804-6707","authenticated-orcid":false,"given":"Ted","family":"Mau","sequence":"additional","affiliation":[{"name":"Clinical Center for Voice Care, Department of Otolaryngology\u2010Head and Neck Surgery University of Texas Southwestern Medical Center Dallas Texas USA"},{"name":"Division of Laryngology, Department of Otolaryngology\u2010Head and Neck Surgery Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.0067"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2024.03.025"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27572"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26762"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817721688"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26390"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941312200309"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26734"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28281"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.20982\/tqmp.04.1.p035"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2019.3072"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/74.4.491"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lary.70308","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lary.70308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T09:40:42Z","timestamp":1777974042000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lary.70308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,12]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/lary.70308"],"URL":"https:\/\/doi.org\/10.1002\/lary.70308","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,12]]},"assertion":[{"value":"2025-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}