{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T02:00:00Z","timestamp":1781143200167,"version":"3.54.1"},"reference-count":69,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T00:00:00Z","timestamp":1770422400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate perioperative changes in olfactory bulb volume (OBV) and olfactory function in patients with eosinophilic chronic rhinosinusitis (ECRS) using 3T magnetic resonance imaging (MRI) with fast imaging employing steady\u2010state acquisition (FIESTA) sequence and to assess their associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center, retrospective observational study included 32 patients with ECRS who underwent functional endoscopic sinus surgery. Olfactory function was assessed pre\u2010 and postoperatively using the Alinamin test, T&amp;T olfactometer, Open Essence (OE), Odor Stick Identification Test for Japanese (OSIT\u2010J), Visual Analog Scale (VAS), and Self\u2010Assessment Olfactory Questionnaire (SAOQ). OBV was manually measured from FIESTA images. Logistic regression was used to identify preoperative predictors of OBV change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Postoperative OE, OSIT\u2010J, VAS, and SAOQ scores improved significantly. Mean OBV increased by 10.3% postoperatively, although not statistically significant (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.095). OBV change correlated with improvements in olfactory identification (OE:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.404,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022; OSIT\u2010J:\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.402,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.022), which should be interpreted as exploratory. Multivariate analysis revealed that longer odor duration on the Alinamin test (\u2265\u200950\u2009s) and higher SAOQ scores predicted smaller OBV increases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OBV measurement using 3T MRI with FIESTA may provide a structural correlate of olfactory changes in ECRS. The observed correlation between OBV changes and olfactory identification suggests a potential relationship with postoperative functional recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>4.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70415","type":"journal-article","created":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:59:15Z","timestamp":1770512355000},"page":"2900-2912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Olfactory Bulb Volume and Function Recovery in Eosinophilic Chronic Rhinosinusitis"],"prefix":"10.1002","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7758-2254","authenticated-orcid":false,"given":"Keisuke","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Abukawa","sequence":"additional","affiliation":[{"name":"Division of Radiology and Nuclear Medicine Sapporo Medical University Hospital, Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Okuni","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Division of Radiology and Nuclear Medicine Sapporo Medical University Hospital, Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Division of Radiology and Nuclear Medicine Sapporo Medical University Hospital, Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Yama","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Ogasawara","sequence":"additional","affiliation":[{"name":"Division of Microbiology, Department of Infectious Diseases Sapporo Medical University School of Medicine  Sapporo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Kamekura","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Sapporo Medical 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