{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:46:05Z","timestamp":1792053965640,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate demographic differences in the association between chronic rhinosinusitis (CRS) symptoms and endoscopic findings with CT\u2010confirmed CRS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive adult patients presenting to outpatient rhinology clinics with chronic cardinal sinonasal symptoms who underwent nasal endoscopy and a sinus CT scan were included. Demographics, cardinal symptoms, SNOT\u201022, and Lund\u2013Kennedy (LK) endoscopic scores were extracted from electronic medical records. Logistic regression was used to assess associations between predictors and CT\u2010confirmed CRS (CT\u2010CRS) with prespecified stratified analyses by race and ethnicity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 314 included patients (mean age 48\u2009\u00b1\u200917\u2009years, 51% female), 228 met criteria for CT\u2010CRS. Hyposmia and LK endoscopic scores were associated with CT\u2010CRS. However, in subgroup analyses, the associations of hyposmia and LK endoscopic scores with CT\u2010CRS were not significant among Asian and Hispanic patients. Among patients with a negative nasal endoscopy, 62.6% had CT\u2010CRS. In this subgroup, patient\u2010reported nasal discharge and the presence of \u2265\u20092 cardinal symptoms were associated with reduced odds of CT\u2010CRS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Associations between symptoms and nasal endoscopy findings with CT\u2010CRS were not significant among Asian and Hispanic patients, suggesting limitations of symptom and endoscopy\u2010based assessments in these subgroups. Among patients with a negative nasal endoscopy, symptoms demonstrated limited ability to identify CT\u2010CRS. These findings suggest CT imaging could be considered earlier in selected clinical contexts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>3<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70631","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:15:43Z","timestamp":1779250543000},"page":"4719-4727","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Race and Ethnicity Affect Symptom and Endoscopy Associations in\n                    <scp>CT<\/scp>\n                    \u2010Confirmed Chronic Rhinosinusitis"],"prefix":"10.1002","volume":"136","author":[{"given":"Corey","family":"Karp","sequence":"first","affiliation":[{"name":"Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Figueroa","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1853-4460","authenticated-orcid":false,"given":"Jaynelle","family":"Gao","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua S.","family":"Lin","sequence":"additional","affiliation":[{"name":"Caruso Department of Otolaryngology\u2010Head and Neck Surgery, Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zara","family":"Mubin","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Albanese","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7016-4375","authenticated-orcid":false,"given":"Kevin","family":"Hur","sequence":"additional","affiliation":[{"name":"Caruso Department of Otolaryngology\u2010Head and Neck Surgery, Keck School of Medicine University of Southern California  California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4193\/rhino50e2"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.04.012"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0194\u201059980223295\u20107"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010019\u201005320\u2010z"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820972672"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998221114078"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.87760"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43163\u2010024\u201000644\u2010y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/sinusitis5010007"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000045748"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1945892419892157"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21071"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.125602"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813514510"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2021.01.010"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22741"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/19458924211056294"},{"issue":"4","key":"e_1_2_10_19_1","first-page":"183","article-title":"Staging in Rhinosinusitis","volume":"31","author":"Lund V. 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