{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T06:06:31Z","timestamp":1788933991768,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n Hearing loss may contribute to mobility decline, but its relationship with gait in cognitively unimpaired adults and whether it differs by sex is unclear.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n In this cross\u2010sectional study, cognitively unimpaired adults aged 50\u201380\u2009years from the DataCOG study were included. Gait was assessed using the instrumented Timed Up and Go test, and pure\u2010tone audiometry (better\u2010ear PTA exposure). Three prespecified composite gait outcomes (global duration, turning, walking duration) were modeled unadjusted, age\/sex\u2010adjusted, and sex\u2010stratified, with HC3\u2010robust linear regression. The a priori criterion was Holm\u2010adjusted\n p<\/jats:italic>\n \u2009<\u20090.05 across the three composites per model; sensitivity analyses added education, comorbidities\/cognition, high\u2010frequency PTA, and a WHO 20\u2009dB HL threshold. Sex\u2010stratified analyses were also performed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 172 participants were included (119 women; mean age 63.9\u2009\u00b1\u20098.1\u2009years) all with complete exposure, outcome, age, sex, and education data. Unadjusted, worse hearing was associated with poorer performance on all three composites (Holm\n p<\/jats:italic>\n \u2009\u2264\u20090.015). Adjusted for age and sex, global duration was borderline (Holm\n p<\/jats:italic>\n \u2009=\u20090.050) and turning\/walking duration no longer met the Holm\u2010adjusted threshold (Holm\n p<\/jats:italic>\n \u2009=\u20090.064, 0.131). Sex\u2010stratified, age\u2010adjusted estimates were larger in men (\n n<\/jats:italic>\n \u2009=\u200953) than women (\n n<\/jats:italic>\n \u2009=\u2009119), but neither sex reached the Holm\u2010adjusted threshold (men, Holm\n p<\/jats:italic>\n \u2009=\u20090.054; women, Holm\n p<\/jats:italic>\n \u2009\u2265\u20090.459).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Worse peripheral hearing was associated with poorer unadjusted gait performance. Adjustment and multiplicity correction attenuated this to borderline or non\u2010significant, and apparent sex differences did not reach the prespecified threshold. These findings are hypothesis\u2010generating and warrant confirmation.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n 3.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lary.70900","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:12:35Z","timestamp":1788930755000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gait and Hearing Performance in Cognitively Unimpaired Adults: A Sex\u2010Stratifyed Analysis"],"prefix":"10.1002","author":[{"given":"Federico","family":"Mollame","sequence":"first","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-0185","authenticated-orcid":false,"given":"Antonino","family":"Maniaci","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Pegreffi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"},{"name":"Recovery and Functional Rehabilitation Unit Umberto I Hospital Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Salfi","sequence":"additional","affiliation":[{"name":"vEyes NPO Milo Italy"},{"name":"School of Medicine University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Caruso","sequence":"additional","affiliation":[{"name":"vEyes NPO Milo Italy"},{"name":"Department of Electrical, Electronic and Computer Engineering University of Catania Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Gagliano","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Lavalle","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Serretti","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"},{"name":"Oasi Research Institute\u2010IRCCS Troina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8397-3478","authenticated-orcid":false,"given":"Antonina","family":"Luca","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery Kore University of Enna Enna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the DataCog Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/lio2.252","article-title":"Balance and Gait in the Elderly: A Contemporary Review","volume":"4","author":"Osoba M. 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