{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T01:44:52Z","timestamp":1791769492359,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Laryngoscope"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Mucosal grafting has become more established in rhinology. While it is accepted that free mucosal grafts take to bone and vascularized recipient beds, the use of mucosal grafting on the contralateral side during nasal septal perforation (NSP) repair with vascularized flaps is not well recognized, but is an important adjunct to ensure healthy reepithelialization of the contralateral septum.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive patients undergoing endoscopic NSP repair with a contralateral free mucosal graft between 2014 and 2025 were included. Grafts were placed opposite the flap on a collagen matrix interlay. The primary outcome was the integration of the free graft judged as complete, partial, or failed. Secondary outcomes included the overall anatomical closure, Miglani endoscopic score, and nasal symptoms assessed via the SNOT\u201022 nasal subdomain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety patients (age 44.3\u2009\u00b1\u200915.5\u2009years; 56.7% male) were followed up for a median of 4.0 [2.0\u20137.0] months. Most repairs utilized an anterior ethmoidal artery flap (95.6%). Free graft integration was complete in 85.6% of all cases (6.7% partial). Anatomical closure was achieved in 90.0% and free graft integration was complete in 92.6% of those patients. Preoperative vs. postoperative endoscopic assessment (3.0 [2.0\u20135.0] vs. 0.0 [0.0\u20131.0],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and nasal subdomain scores improved significantly (9.0 [6.0\u201314.0] vs. 4.0 [2.0\u201310.0],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Contralateral free mucosal grafts heal reliably in endoscopic NSP repair, with complete healing in over 93% of patients with successful closure. The technique is simple to perform and assists in achieving rapid reepithelialization in an area at high risk of desiccation and poor healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>4.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lary.70966","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:57:35Z","timestamp":1791766655000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Free Mucosal Grafting Is a Simple Adjunct for Rapid Re\u2010Epithelization in Septal Perforation Repair"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3345-9486","authenticated-orcid":false,"given":"Nicholas J.","family":"Campion","sequence":"first","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Faculty of Medicine and Health Sciences Macquarie University  Sydney Australia"},{"name":"Vienna Airway Lab, Department of Otorhinolaryngology\u2010Head and Neck Surgery General Hospital and Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Miguel","family":"Couto","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Almada\u2010Seixal Local Health Unit  Almada Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8575-9851","authenticated-orcid":false,"given":"Elizabeth","family":"Hua","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Qiao","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9679-3495","authenticated-orcid":false,"given":"Hardip Singh","family":"Gendeh","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Department of Otolaryngology\u2010Head and Neck Surgery, Faculty of Medicine Universiti Kebangsaan Malaysia  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6566-2169","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Rosenbaum Fuentes","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2945-6090","authenticated-orcid":false,"given":"Rhea","family":"Darbari Kaul","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Faculty of Medicine and Health Sciences Macquarie University  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Alvarado","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Choy","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal","family":"Elhage","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peta\u2010Lee","family":"Sacks","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Faculty of Medicine and Health Sciences Macquarie University  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6512-3613","authenticated-orcid":false,"given":"Raewyn G.","family":"Campbell","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Faculty of Medicine and Health Sciences Macquarie University  Sydney Australia"},{"name":"Department of Otolaryngology, Head and Neck Surgery Royal Prince Alfred Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry","family":"Kalish","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Department of Otolaryngology, Head and Neck Surgery Concord General Hospital, University of Sydney  Sydney Australia"},{"name":"Faculty of Medicine University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6942-8975","authenticated-orcid":false,"given":"Richard J.","family":"Harvey","sequence":"additional","affiliation":[{"name":"Rhinology and Skull Base Research Group, St Vincent's Centre for Applied Medical Research University of New South Wales  Sydney Australia"},{"name":"Faculty of Medicine and Health Sciences Macquarie University  Sydney Australia"},{"name":"School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, Faculty of Medicine and Health University of New South Wales  Sydney 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