{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:16:28Z","timestamp":1788437788517,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["T32 DC000018"],"award-info":[{"award-number":["T32 DC000018"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify characteristics associated with successful electrolarynx (EL) use after total laryngectomy (TL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Records of 196 adults who underwent TL from 03\/15\/2012 to 03\/15\/2022 at the University of Washington and Puget Sound Veterans Affairs were reviewed. Characteristics included age, Charlson Comorbidity Index, social support, pre\u2010operative radiation (RT) and chemoradiation (CRT), and 6\u2010month post\u2010TL swallow status. EL success was evaluated using pre\u2010defined criteria of intelligibility, reliability, and independence with use. Poisson regressions and robust standard error estimates were used to estimate unadjusted risk ratios for each characteristic. Statistically significant characteristics were included in multivariate analysis (MVA) to estimate adjusted risk ratios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median age was 64, median Charlson Comorbidity Index was 5, 170 (87%) were male, 159 (81%) had high social support, and 159 (81%) attained post\u2010TL full\u2010oral diet. Pre\u2010operatively, 110 (56%) had RT, including 55 (28%) with CRT. Ninety\u2010three (47%) met our criteria for EL success. Characteristics significantly associated with EL success included social support (<jats:italic>p<\/jats:italic>\u2009=\u2009.037) and post\u2010TL full\u2010oral diet (<jats:italic>p<\/jats:italic>\u2009=\u2009.037); both approached significance on MVA. EL success varied by pre\u2010operative treatment on univariate (<jats:italic>p<\/jats:italic>\u2009=\u2009.005) and MVA (<jats:italic>p<\/jats:italic>\u2009=\u2009.014). Compared to no prior RT or CRT, the probability of EL success was 29% higher with prior RT and 29% lower with prior CRT in MVA, although these associations did not reach significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this retrospective review, EL success correlated with high social support, post\u2010TL full\u2010oral diet, and pre\u2010operative treatment history. These results warrant validation in a larger prospective study to help guide the choice of voice rehabilitation modalities or intensified speech therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.1212","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T09:00:48Z","timestamp":1706000448000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Factors associated with successful electrolarynx use after total laryngectomy, a multi\u2010institutional study"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2776-4679","authenticated-orcid":false,"given":"Cassie","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah I. B.","family":"Andrews","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Veterans Affairs Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neel K.","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2070-2005","authenticated-orcid":false,"given":"Zain H.","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery University of Washington  Seattle Washington USA"},{"name":"Department of Veterans Affairs Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"1","article-title":"Functional outcomes following treatment for advanced laryngeal cancer. Part I\u2010\u2010voice preservation in advanced laryngeal cancer. Part II\u2010\u2010laryngectomy rehabilitation: the state of the art in the VA system. Research speech\u2010language pathologists. Department of Veterans Affairs Laryngeal Cancer Study Group","volume":"172","author":"Hillman RE","year":"1998","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/MDER.S133225"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010009\u20101138\u2010x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814524704"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1726\u20104901(08)70030\u20103"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.126.11.1320"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348949510400404"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1808\u20108694(15)31207\u20106"},{"issue":"4","key":"e_1_2_9_10_1","first-page":"452","article-title":"Tracheoesophageal puncture outcomes and predictors of success in laryngectomised patients","volume":"29","author":"Saurajen AS","year":"2000","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1994.01880270047009"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100039\u20103402497"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510800371X"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.2409"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813502310"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0936\u20106555(05)80064\u20100"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/000164802760057716"},{"issue":"6","key":"e_1_2_9_18_1","first-page":"360","article-title":"Voice rehabilitation in laryngectomees: comparison of daily\u2010life performance of 4 types of alaryngeal speech","volume":"66","author":"Tsai TL","year":"2003","journal-title":"J Chin Med Assoc"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050000299"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.1212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T12:11:42Z","timestamp":1708690302000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.1212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,23]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1002\/lio2.1212"],"URL":"https:\/\/doi.org\/10.1002\/lio2.1212","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,23]]},"assertion":[{"value":"2023-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e1212"}}