{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:42:06Z","timestamp":1792017726921,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the relationship between various electrodiagnostic modalities in acute facial palsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic tertiary care center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>One\u2010hundred and six patients who presented with traumatic or non\u2010traumatic acute facial paralysis (House\u2010Brackmann, HB, grade 6\/6) between 2008 and 2017 and underwent acute electrodiagnostic testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>Electroneurography (ENoG) using nasolabial fold (NLF) or nasalis muscle (NM) methods, and volitional electromyography (EMG) in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Percent degeneration of ipsilateral facial nerve compound muscle action potentials (CMAP) on NLF\u2010 and NM\u2010ENoG, presence or absence of muscle unit potentials (MUPs) on EMG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Extent of facial nerve degeneration measured by NLF\u2010 and NM\u2010ENoG were highly correlated (<jats:italic>r<\/jats:italic> = 0.85, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) on each test and on serial testing. NLF\u2010 and NM\u2010ENoG concordantly diagnosed \u226590% degeneration in 44 patients (80%), of whom 32 patients were diagnosed to have 100% degeneration by both methodologies. Absence of MUPs on EMG was 63% sensitive and 92% specific for \u226590% degeneration on ENoG, with a positive predictive value of 90%. For patients with Bell's palsy, percent degeneration on ENoG was also correlated to HB score at 1 year. Surgical decompression resulted in mean HB scores of 2.2 and 3.0 for patients with Bell's palsy and trauma, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>NM\u2010ENoG may be a valid and comparable method to NLF\u2010ENoG for predicting the recovery of facial nerve function in acute paralysis. Absence of MUPs on EMG is a specific measure of severe degeneration and highly predictive of candidacy for surgical decompression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Level 3.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.458","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T22:16:01Z","timestamp":1601331361000},"page":"928-935","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Electrodiagnostic testing in acute facial palsy: Outcomes and comparison of methods"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9753-0512","authenticated-orcid":false,"given":"Nicholas S.","family":"Andresen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Johns Hopkins University School of Medicine  Baltimore Maryland 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