{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:00:58Z","timestamp":1789423258906,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["K23AG059900"],"award-info":[{"award-number":["K23AG059900"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["2T32DC000027\u201031A1"],"award-info":[{"award-number":["2T32DC000027\u201031A1"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To perform a systematic review to determine if a total score of \u226514.5 (mean score\u2009\u2265\u20092.1) on the ETDQ\u20107 accurately identifies patients with obstructive Eustachian tube dysfunction (OETD) on impedance tympanometry (peak compliance &lt;0.2\u00a0mL or middle ear pressure of \u2212100\u2009daPa) or other objective measures of OETD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review without a meta\u2010analysis was performed of studies in four electronic databases (Pubmed, Embase, Web of Science, and Scopus) that used the ETDQ\u20107 and at least one objective measure of OETD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six\u2010hundred and fifty\u2010two studies were identified in the initial literature search. Abstracts from 337 studies were screened, followed by full\u2010text review of 61 studies, and qualitative synthesis of 12 studies. Tympanometry was used as an objective measure in ten studies. Eight of the 12 included studies had patient cohort selection bias. Eight studies administered the ETDQ\u20107 in cohorts of patients with or without OETD, already confirmed on tympanometry, and found a sensitivity of 91%\u2010100% and specificity of 67%\u2010100%. Four studies administered the ETDQ\u20107 to patients who had not previously undergone objective testing and found a sensitivity of 49%\u201080% and specificity of 24%\u201078%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ETDQ\u20107 is an important patient\u2010reported outcome measure. However, based upon existing literature, the ETDQ\u20107 appears limited as a diagnostic tool for OETD or as an objective measure of Eustachian tube function.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.606","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T11:40:11Z","timestamp":1624534811000},"page":"844-851","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Predictive value of the Eustachian Tube Dysfunction Questionnaire\u20107 for identifying obstructive Eustachian tube dysfunction: A systematic review"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9753-0512","authenticated-orcid":false,"given":"Nicholas S.","family":"Andresen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Johns Hopkins University School of Medicine  Baltimore Maryland 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