{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T10:20:54Z","timestamp":1785320454409,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T00:00:00Z","timestamp":1734134400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["1K08DC020761\u201001"],"award-info":[{"award-number":["1K08DC020761\u201001"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Malignant otitis externa (MOE) is typically managed with long\u2010term broad\u2010spectrum antibiotics. The impact of surgical intervention on clinical outcomes is not well described. This study aims to compare clinical outcomes of MOE patients managed with or without surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design\/Setting<\/jats:title><jats:p>Retrospective cohort, academic tertiary referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients diagnosed with MOE between January 2010 to September 2022 were included. Univariate analyses compared symptoms at initial presentation and long\u2010term (\u22651\u2009year) outcomes between surgical and non\u2010surgical patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 23 patients were included (78% male, mean age 69\u2009\u00b1\u200913\u2009years, median follow\u2010up 305\u2009days). Most (<jats:italic>N<\/jats:italic>\u2009=\u200922, 96%) patients were diabetic. Seventeen (74%) underwent surgical intervention (76% tympanomastoidectomy, 24% external auditory canal debridement and biopsy). Poor facial nerve (FN) function at initial presentation (defined as House\u2010Brackmann [HB] grade\u2009\u22653) significantly predicted undergoing surgical intervention (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). Comparing surgically managed versus non\u2010surgical patients at the time of presentation, there were no differences in the degree of hearing loss, severity of diabetes, rate of insulin dependence, incidence of immunosuppression, or the Charlson Comorbidity Index (all <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). FN outcomes at long\u2010term follow\u2010up also did not significantly differ (p\u2009&gt;\u20090.05). No significant differences in the length of stay (9 vs. 6\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.2), rate of readmission (31% vs. 17%, <jats:italic>p<\/jats:italic>\u2009=\u20090.5) or 5\u2010year overall survival (53% vs. 66%, <jats:italic>p<\/jats:italic>\u2009=\u20090.6) were observed between surgical and non\u2010surgical patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Long\u2010term outcomes for patients with MOE remain poor. Patients with poor FN function at presentation were more likely to undergo surgical intervention. Patient comorbidities, including the severity of diabetes, were not predictive of undergoing surgery. However, surgical intervention for MOE did not appear to lower the length of stay, the rate of hospital readmission, or overall mortality in our cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>III<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.70029","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T08:43:57Z","timestamp":1734165837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Malignant otitis externa: What is the role of surgery?"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-2048","authenticated-orcid":false,"given":"Lisa","family":"Zhang","sequence":"first","affiliation":[{"name":"Division of Otology, Neurotology and Cranial Base Surgery, Department of Otolaryngology\u2010Head and Neck Surgery The Ohio State University Wexner Medical Center  Columbus Ohio 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Department of Otolaryngology\u2010Head and Neck Surgery The Ohio State University Wexner Medical Center  Columbus Ohio 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