{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T10:14:25Z","timestamp":1770286465330,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,11,17]],"date-time":"2024-11-17T00:00:00Z","timestamp":1731801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to document and analyze the challenges and outcomes of performing complex airway surgery in a low\u2010resource, post\u2010war setting in Mekelle, Ethiopia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective case series examines clinical data from five patients who underwent airway reconstruction surgeries and one patient who underwent total laryngectomy at Ayder Comprehensive Specialized Hospital in Mekelle. Data included patient demographics, airway stenosis etiology and severity, operative details, postoperative outcomes, complications, and hospital length of stay. Ethical approval was obtained from institutional review boards at Mayo Clinic and Mekelle University.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included six patients aged 9\u201362\u2009years, with surgeries comprising three cricotracheal resections, two tracheal resections, and one laryngectomy. Three reconstructions were for war\u2010related injuries. Challenges included power outages during surgeries, limitations in medical supplies and equipment, and inadequate perioperative care. Despite these, three patients requiring tracheostomies were successfully decannulated within a year. However, complications such as restenosis, infections, and the need for reintubation were common.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Airway surgeries in a low\u2010resource, post\u2010war setting face significant hurdles, including perioperative care quality, resource limitations, and infrastructure issues. Successful outcomes require multidisciplinary training tailored to local contexts, investments in hospital infrastructure and reliable electricity, and proper perioperative nutrition. This study highlights the need for comprehensive interventions to improve surgical care in such settings.<\/jats:p><jats:p><jats:bold>Level of evidence:<\/jats:bold> IV.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.70034","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T07:34:22Z","timestamp":1731915262000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Challenges and outcomes of airway surgery in a post\u2010war low\u2010resource setting: A case series from Mekelle, Ethiopia"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2195-5243","authenticated-orcid":false,"given":"Daniel G.","family":"Eyassu","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3002-7071","authenticated-orcid":false,"given":"Estephania","family":"Candelo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery University of Washington School of Medicine  Seattle Washington USA"},{"name":"Centro de Investigaciones Clinicas, Fundacion Valle del Lili  Cali Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6322-1124","authenticated-orcid":false,"given":"Brhanu H.","family":"Asgedom","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery Ayder Comprehensive Specialized Hospital  Mekele Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8274-0971","authenticated-orcid":false,"given":"Katherine P.","family":"Wallerius","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaina W.","family":"Twardus","sequence":"additional","affiliation":[{"name":"University of Virginia School of Medicine  Charlottesville Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7580-8731","authenticated-orcid":false,"given":"Weston L.","family":"Niermeyer","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology and Head and Neck Surgery The George Washington University School of Medicine and Health Sciences  Washington, DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5937-4822","authenticated-orcid":false,"given":"Katerina J.","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6336-0826","authenticated-orcid":false,"given":"Tejas S.","family":"Athni","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7377-7107","authenticated-orcid":false,"given":"Joshua P.","family":"Wiedermann","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1271028"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104\u2010023\u201006640\u20104"},{"key":"e_1_2_9_4_1","unstructured":"Ethiopia's Tigray crisis: \u201cHow we survived when Mekelle was shelled\u201d.https:\/\/www.bbc.com\/news\/world-africa-55325603. 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