{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T12:46:03Z","timestamp":1782823563088,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Examine improvements in hearing and tinnitus\u2010related quality\u2010of\u2010life metrics that occur after cochlear implant surgery in patients with single\u2010sided deafness (SSD) and asymmetric hearing loss (AHL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult patients undergoing cochlear implant surgery for SSD or AHL during a 2\u2010year period at a quaternary academic medical center completed the validated survey instruments tinnitus functional index (TFI) and Speech, Spatial, and Qualities of Hearing Scale (SSQ) before surgery, and at least 3\u2009months after cochlear implant activation. Standardized protocols for audiometric assessment were completed pre\u2010 and postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010four patients met inclusion criteria and had complete audiometric and survey data. Overall, composite TFI score improved significantly from a mean severity of 48.2\u2009\u00b1\u20099.2\u201318.6\u2009\u00b1\u20096.53; after cochlear implantation (<jats:italic>q<\/jats:italic>\u2009=\u20092.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and there was statistically significant improvement in all eight subdomains of the TFI after surgery. The SSQ composite scores significantly improved from a mean of 2.5\u2009\u00b1\u20090.30\u20135.07\u2009\u00b1\u20090.44 after CI (<jats:italic>q<\/jats:italic>\u2009=\u20092.01, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). All three subdomains of the SSQ improved significantly after cochlear implantation though the magnitude of the changes were higher for Speech Hearing and Spatial Hearing compared with the Qualities of Hearing domain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cochlear implantation surgery in patients with SSD or AHL leads to significant overall improvements in hearing related quality of life, but particularly in the areas of speech understanding, spatial aspects of hearing, and tinnitus severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>3<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.70090","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T10:44:15Z","timestamp":1745318655000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Speech, Spatial, and Qualities of Hearing Scale and Tinnitus Functional Index Improvements After Cochlear Implant Surgery for Single\u2010Sided Deafness"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3658-9457","authenticated-orcid":false,"given":"Scott B.","family":"Shapiro","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery &amp; Communication Sciences Rutgers Robert Johnson Medical School  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7727-6353","authenticated-orcid":false,"given":"Todd M.","family":"Mowery","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery &amp; Communication Sciences Rutgers Robert Johnson Medical School  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2904-5072","authenticated-orcid":false,"given":"P. Ashley","family":"Wackym","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery &amp; Communication Sciences Rutgers Robert Johnson Medical School  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003760"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998221083283"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9041010"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216518813802"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/2331216518771173"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000548"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002235"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003833"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000430"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000484079"},{"key":"e_1_2_7_12_1","unstructured":"US Food and Drug Administration \u201cMED\u2010EL Cochlear Implant System PMA Supplement Approval Letter \u201d2019 https:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf\/P000025S104A.pdf."},{"key":"e_1_2_7_13_1","unstructured":"US Food and Drug Administration \u201cNucleus 24 Cochlear Implant System PMA Supplement Approval Letter \u201d2020 https:\/\/www.accessdata.fda.gov\/cdrh_docs\/pdf\/P970051S172A.pdf."},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-016-0297-5"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000490879"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000000671"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000380751"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06411-y"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28358"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000707"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000171478"},{"key":"e_1_2_7_22_1","article-title":"Cochlear Implants in Single\u2010Sided Deafness\u2014Clinical Results of a Swiss Multicentre Study","volume":"149","author":"Peter N.","year":"2019","journal-title":"Swiss Medical Weekly"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001520"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000951"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001043"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000000102"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488755"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002564"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0b013e31822f67c0"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/audiolres13010003"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890140029007"},{"issue":"2","key":"e_1_2_7_32_1","first-page":"153","article-title":"Psychometric Adequacy of the Tinnitus Handicap Inventory (THI) for Evaluating Treatment Outcome","volume":"9","author":"Newman C. 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