{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:36Z","timestamp":1786978116950,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To achieve glottal gap closure in unilateral vocal fold paralysis (UVFP) through complementary ansa cervicalis nerve muscle pedicle laryngeal reinnervation (ANMP\u2010LR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>ANMP\u2010LR is easy to learn and does not require recurrent laryngeal nerve (RLN) transection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Twelve patients with unilateral vocal fold paralysis (UVFP) were included, who received ANMP\u2010LR and could be followed up for at least 6\u201324\u2009months. At baseline, after 3\u20136 (T1), 12 (T2) and 24\u2009months (T3), Voice Handicap Index (VHI), perceived roughness (R) and breathiness (B), sound pressure level (SPLmax), maximum phonation time (MPT), Dysphonia Severity Index (DSI) and glottal gap (GG) were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>R and B were significantly reduced at T1, MPT and SPLmax increased significantly up to T1 (MPT to 15.8\u2009s; SPLmax to 91.5\u2009dB). Similarly, VHI dropped significantly and the residual glottal gap (GG) was significantly reduced between T0 and T1. All outcomes remained stable until T3. There was a non\u2010significant tendency to further improvement until T3 in SPLmax and GG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The T1\u2013T3 outcomes of the complementary ANMP\u2010LR are comparable with the standard LR and also with thyroplasty. As with all LR techniques, younger patients and those with shorter paralysis benefit more. Patients with evidence of unfavorable laryngeal synkinesis are more likely to benefit from a standard LR with RLN transection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Younger patients with insufficient synkinetic reinnervation and persisting or progressive glottis closure insufficiency in UVFP benefit from early reinnervation. When the easy\u2010to\u2010learn ANMP technique is used, any partial rehabilitation that has already been achieved or any remaining chance of spontaneous reinnervation via the RLN is not compromised.<\/jats:p>\n                    <jats:p>Level of Evidence: 3<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70104","type":"journal-article","created":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T03:16:46Z","timestamp":1740539806000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Complementary Reinnervation in Unilateral Vocal Fold Paralysis"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-5527","authenticated-orcid":false,"given":"Andreas H.","family":"Mueller","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\/Plastic Surgery SRH Wald\u2010Klinikum Gera  Gera Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4315-569X","authenticated-orcid":false,"given":"Kathleen","family":"Klinge","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Plastic Surgery SRH Wald\u2010Klinikum Gera  Gera Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6806-1289","authenticated-orcid":false,"given":"Gerhard","family":"Foerster","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Plastic Surgery SRH Wald\u2010Klinikum Gera  Gera Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1353-5688","authenticated-orcid":false,"given":"Fabian","family":"Burk","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Plastic Surgery SRH Wald\u2010Klinikum Gera  Gera Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"e_1_2_7_2_1","article-title":"Experiences of Patients With Unilateral Vocal Fold Paralysis: A Mixed\u2010Methods Study of the Insider's Perspective","author":"Kissel I.","year":"2024","journal-title":"Journal of Voice"},{"key":"e_1_2_7_3_1","first-page":"S144","article-title":"Active and Passive Bioimplants for Vocal Fold Paralysis","volume":"101","author":"Mueller A. H.","year":"2022","journal-title":"Laryngo\u2010 Rhino\u2010 Otologie"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000496491"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10001-1517"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5152\/B-ENT.2023.231247"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21754"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2020.08.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2019.09.017"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.1991.101.4.384"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28324"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000456688"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600612"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.155"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26032"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26323"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000004124"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010012\u20102036\u20101"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.3303.601"},{"key":"e_1_2_7_20_1","unstructured":"L.Servier \u201cLarynx. Available at: Laboratoires Servier: Otorhinolaryngology\u2014Larynx\u2014Smart\u2010Servier.png \u201dhttps:\/\/commons.wikimedia.org\/w\/index.php?curid=128146017 under the CC BY\u2010SA 3.0 licence https:\/\/creativecommons.org\/licenses\/by\u2010sa\/3.0\/."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050000299"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010023\u201008211\u20106"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106\u2010003\u20100909\u20108"},{"key":"e_1_2_7_24_1","volume-title":"Clinical Examination of Voice","author":"Hirano M.","year":"1981"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2811"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.6.4.284"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2012.06.003"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3418-3"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13775"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2014.01.010"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-022-07437-0"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010016871"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2013.01.009"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010014\u20103091\u20106"},{"key":"e_1_2_7_37_1","first-page":"471","volume-title":"Laryngeal Reinnervation for Unilateral Vocal Fold Paralysis Operative Techniques in Laryngology","author":"Paniello R. C.","year":"2024"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24623"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348940010900405"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2022.04.010"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,8]],"date-time":"2025-03-08T12:57:55Z","timestamp":1741438675000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.70104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/lio2.70104"],"URL":"https:\/\/doi.org\/10.1002\/lio2.70104","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70104"}}