{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T04:48:17Z","timestamp":1781758097189,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the clinical characteristics and prognostic factors influencing treatment outcomes in pediatric sudden sensorineural hearing loss (PSSNHL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was conducted on 63 children (64 ears) diagnosed with PSSNHL from January 2013 to December 2023. All patients received either systemic or intra\u2010tympanic steroid therapy. Data on age, tinnitus presence, audiogram types, and initial hearing thresholds were analyzed using SPSS 25.0. Univariate and multivariate logistic regressions were performed to identify significant prognostic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age was 16\u2009years (interquartile range:14\u201317\u2009years). Median time from symptom onset to treatment was 7\u2009days (interquartile range: 4\u201313\u2009days). Tinnitus was present in 85.7% of cases. Post\u2010treatment hearing thresholds improved from 84.52\u2009\u00b1\u20093.29\u2009dB HL to 64.17\u2009\u00b1\u20094.48\u2009dB HL (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The overall therapeutic efficacy rate was 48.4%. Multivariate analysis identified time from onset to treatment (OR\u2009=\u20090.923; 95% CI: 0.789\u20130.997; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) and initial hearing threshold (OR\u2009=\u20090.939; 95% CI: 0.869\u20130.981; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) as independent prognostic factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Early intervention and lower initial hearing thresholds are associated with a better prognosis in PSSNHL. Prompt treatment significantly improves outcomes, highlighting the importance of early diagnosis and intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>Level 4.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.70112","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T13:44:37Z","timestamp":1744292677000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic Factors and Clinical Characteristics in Pediatric Sudden Sensorineural Hearing Loss: A Retrospective Analysis"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1462-9178","authenticated-orcid":false,"given":"Ranshi","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Southwest Hospital, Army Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoling","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Southwest Hospital, Army Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3346-0578","authenticated-orcid":false,"given":"Cheng","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Southwest Hospital, Army Medical University  Chongqing 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