{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T20:06:07Z","timestamp":1793131567882,"version":"4.5.0"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201022\u2010CE52\u20100006"],"award-info":[{"award-number":["ANR\u201022\u2010CE52\u20100006"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR\u201023\u2010IAHU\u20100003"],"award-info":[{"award-number":["ANR\u201023\u2010IAHU\u20100003"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Rodents are used in most otological research studies and the choice of the most appropriate animal model may be crucial in studies of ear diseases and in the development of effective treatments. Here, we used micro\u2010CT to compare temporal bone anatomy between four rodent model animals (guinea pigs, gerbils, rats, and mice) and humans, aiming to better characterize the anatomy of the inner and middle ear, and facial nerve to support informed animal model selection in otologic research.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We generated three\u2010dimensional reconstructions and measured the various middle (tympanic membrane, ossicular chain, and facial nerve) and inner (cochlea, vestibular labyrinth) ear structures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Each structure of the middle or inner ear of each rodent was described and measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This micro\u2010CT analysis of rodents can guide researchers in their choice of the most suitable middle or inner ear models based on the specific anatomic area of interest. Our findings highlight the strengths and limitations of each species, providing essential insight that could enhance the precision and applicability of otological studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>4.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70190","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T01:12:37Z","timestamp":1750813957000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Micro\u2010\n                    <scp>CT<\/scp>\n                    Analysis of Rodent Temporal Bones: Identifying Optimal Species for Otological Research"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7826-0721","authenticated-orcid":false,"given":"Hannah","family":"Daoudi","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Pasteur, AP\u2010HP, Inserm, Fondation Pour l'audition, Institut de l'audition, IHU Re\u2010Connect F\u201075012, Technologies and Gene Therapy for Deafness  Paris France"},{"name":"ENT Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Ferrary","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Pasteur, AP\u2010HP, Inserm, Fondation Pour l'audition, Institut de l'audition, IHU Re\u2010Connect F\u201075012, Technologies and Gene Therapy for Deafness  Paris France"},{"name":"ENT Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cerine","family":"Moula","sequence":"additional","affiliation":[{"name":"Paris\u2010Saclay University, CNRS, Galien Paris\u2010Saclay Institute  Orsay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Agnely","sequence":"additional","affiliation":[{"name":"Paris\u2010Saclay University, CNRS, Galien Paris\u2010Saclay Institute  Orsay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Bochot","sequence":"additional","affiliation":[{"name":"Paris\u2010Saclay University, CNRS, Galien Paris\u2010Saclay Institute  Orsay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cailleau","sequence":"additional","affiliation":[{"name":"Paris\u2010Saclay University, CNRS, Galien Paris\u2010Saclay Institute  Orsay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Pasteur, AP\u2010HP, Inserm, Fondation Pour l'audition, Institut de l'audition, IHU Re\u2010Connect F\u201075012, Technologies and Gene Therapy for Deafness  Paris France"},{"name":"ENT Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1067-045X","authenticated-orcid":false,"given":"Ghizl\u00e8ne","family":"Lahlou","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Pasteur, AP\u2010HP, Inserm, Fondation Pour l'audition, Institut de l'audition, IHU Re\u2010Connect F\u201075012, Technologies and Gene Therapy for Deafness  Paris France"},{"name":"ENT Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6701-6793","authenticated-orcid":false,"given":"Renato","family":"Torres","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Pasteur, AP\u2010HP, Inserm, Fondation Pour l'audition, Institut de l'audition, IHU Re\u2010Connect F\u201075012, Technologies and Gene Therapy for Deafness  Paris France"},{"name":"ENT Department, Piti\u00e9\u2010Salp\u00eatri\u00e8re, APHP Sorbonne University  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1808\u20108694(15)30830\u20102"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102\u201086502004000400014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348947508400220"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429\u2010016\u20101259\u20100"},{"issue":"5","key":"e_1_2_9_6_1","first-page":"438","article-title":"Surgical Anatomy of the Rat Middle Ear","volume":"117","author":"Judkins R. 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