{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T05:10:13Z","timestamp":1756444213469,"version":"3.44.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the differences in the symptoms associated with common otolaryngology complaints between male and female patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between June 2020 and July 2023, a multi\u2010institutional cross\u2010sectional study was performed at six tertiary academic otolaryngology practices using semantics\u2010based questionnaires to assess the symptoms patients associate with the complaints of sinus infection, reflux, congestion, and dizziness. Patients selected symptoms from lists of proposed terms to describe the various conditions. The primary outcome measure was sex\u2010related differences in respondent symptom selection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four separate questionnaires were completed by a total of 1495 patients (46.0% male, 54.0% female). Female patients more often described sinus infection using pain\u2010related symptoms (difference 8.8%; 95% CI, 2.8% to 14.8%) and systemic\u2010related symptoms (difference 10.2%; 95% CI, 2.3% to 18.2%), reflux using pain\u2010related symptoms (difference 18.3%; 95% CI, 3.6% to 41.7%) and sensory\u2010related symptoms (difference 13.1%; 95% CI, 2.5% to 23.7%), and dizziness using vision\u2010related symptoms (13.2%; 95% CI, 1.9% to 24.6%) compared to male patients. Female patients selected individual symptoms within the pain\u2010related domain more often than male patients to describe congestion. Few differences per questionnaire were identified based on geographic location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sex\u2010related differences exist in how patients describe common otolaryngologic complaints. Women more commonly associate pain\u2010related symptoms with sinus infection and reflux, sensory\u2010related symptoms with reflux, and vision\u2010related symptoms with dizziness. A more nuanced understanding of how men and women describe complaints may lead to more effective, patient\u2010centered care within otolaryngology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.70235","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T15:10:12Z","timestamp":1755270612000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sex\u2010Related Variability in the Perception of Symptoms Associated With Common Otolaryngologic Complaints"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6092-4785","authenticated-orcid":false,"given":"Sabrina K.","family":"Wagner","sequence":"first","affiliation":[{"name":"School of Medicine Uniformed Services University of the Health Sciences  Bethesda Maryland 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