{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T20:38:07Z","timestamp":1769891887386,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2025,12]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n \n This study seeks to characterize the impact of\n COVID<\/jats:styled-content>\n \u201019 infection on endoscopic sinus surgery (\n ESS<\/jats:styled-content>\n ) outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The\n TriNetX<\/jats:styled-content>\n database identified patients with chronic rhinosinusitis who underwent\n ESS<\/jats:styled-content>\n from January 1, 2020 to December 31, 2024. Cohorts included patients who had a diagnosis of\n COVID<\/jats:styled-content>\n \u201019 infection within 2 months before\n ESS<\/jats:styled-content>\n (recent infection), and those who did not. A cohort of those with\n COVID<\/jats:styled-content>\n \u201019 infection between 2 months and 1 year before\n ESS<\/jats:styled-content>\n (distant infection), was compared to a control without recent or distant infection. Propensity score matching (\n PSM<\/jats:styled-content>\n ) controlled for demographics and comorbid conditions. Relative risks (\n RRs<\/jats:styled-content>\n ) were calculated to determine risks for postoperative complications and healthcare utilization.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 49,609 patients underwent\n ESS<\/jats:styled-content>\n during the study period. After\n PSM<\/jats:styled-content>\n , there were 10,803 patients with and without recent\n COVID<\/jats:styled-content>\n \u201019 infection, and 3804 patients with or without distant\n COVID<\/jats:styled-content>\n \u201019 infection. Recent\n COVID<\/jats:styled-content>\n \u201019 infection increased the risk of epistaxis [\n RR<\/jats:styled-content>\n : 1.236, 95%\n CI<\/jats:styled-content>\n : (1.036, 1.474)], and nasal congestion [\n RR<\/jats:styled-content>\n : 1.273, 95%\n CI<\/jats:styled-content>\n : (1.016, 1.596)] within 2\u2009months of\n ESS<\/jats:styled-content>\n . There was no difference in risk for major complications identified between any cohort.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Recent\n COVID<\/jats:styled-content>\n \u201019 infection may increase the risk of post\u2010operative epistaxis, but not major complications, highlighting the overall safety of\n ESS<\/jats:styled-content>\n after recent\n COVID<\/jats:styled-content>\n \u201019 infection and the importance of considering the timing of\n COVID<\/jats:styled-content>\n \u201019 infection when evaluating surgical risk and postoperative care needs for\n ESS<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>\n \n Level of Evidence<\/jats:title>\n Level III.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lio2.70326","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:36:16Z","timestamp":1766147776000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the Safety of Endoscopic Sinus Surgery After\n COVID<\/scp>\n \u201019 Infection"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8355-4804","authenticated-orcid":false,"given":"Ella Prebel","family":"Jackert","sequence":"first","affiliation":[{"name":"Keck School of Medicine University of Southern California Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4824-7160","authenticated-orcid":false,"given":"Oluwatobiloba","family":"Ayo\u2010Ajibola","sequence":"additional","affiliation":[{"name":"Keck School of Medicine University of Southern California Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric X.","family":"Wei","sequence":"additional","affiliation":[{"name":"Vanderbilt University Department of Otolaryngology\u2010Head & Neck Surgery Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"issue":"11","key":"e_1_2_10_2_1","first-page":"1440","article-title":"Elective Surgery Cancellations due to the COVID\u201019 Pandemic: Global Predictive Modelling to Inform Surgical Recovery Plans","volume":"107","author":"COVIDSurg Collaborative","year":"2020","journal-title":"British Journal of Surgery"},{"key":"e_1_2_10_3_1","volume-title":"American Society of Anesthesiologists and Anesthesia Patient Safety Foundation Joint Statement on Elective Surgery\/Procedures and Anesthesia for Patients After COVID\u201019 Infection","author":"American Society of 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