{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:53:20Z","timestamp":1781877200106,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["2023YFC2508400"],"award-info":[{"award-number":["2023YFC2508400"]}],"id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["2023YFF1203504"],"award-info":[{"award-number":["2023YFF1203504"]}],"id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the association of vertigo with rates of frequency\u2010specific hearing recovery in pediatric and adult patients with unilateral idiopathic sudden sensorineural hearing loss (SSNHL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 80 pediatric and 444 adult patients hospitalized with SSNHL were included in this study. Clinical and audiological data were collected, and frequency\u2010specific hearing recovery percentages before and after treatment were compared between pediatric and adult SSNHL patients with and without vertigo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In pediatric SSNHL patients with vertigo, the median recovery rates at 250\u2013500\u2009Hz, 1000\u20132000\u2009Hz, and 4000\u20138000\u2009Hz were 62.5%, 28.2%, and 21.1%, respectively, whereas those without vertigo showed higher median recovery rates of 90.3%, 82.1%, and 56.5%. Similarly, adult SSNHL patients with vertigo exhibited median recovery rates of 53.2%, 33.7%, and 24.6% across the same frequency ranges, compared to 88.9%, 76.6%, and 53.3% in adults without vertigo. In both pediatric and adult cohorts, hearing recovery decreased progressively with increasing frequency. Patients with vertigo exhibited consistently lower recovery across all frequency bands compared to those without vertigo. However, no statistically significant differences in frequency\u2010specific recovery were observed between pediatric and adult SSNHL cohorts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The incidence of vertigo increases with the severity of hearing loss in SSNHL ranging from moderately severe to total deafness. Vertigo is a prognostic factor associated with poorer hearing recovery across all frequencies, underscoring its importance as a critical clinical indicator in the management of SSNHL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>3<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70391","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T07:15:45Z","timestamp":1775286945000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Prognostic Analysis of Sudden Sensorineural Hearing Loss With Vertigo in Pediatric and Adult Patients"],"prefix":"10.1002","volume":"11","author":[{"given":"Changshuo","family":"Shan","sequence":"first","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dayong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3747-0327","authenticated-orcid":false,"given":"Qiuju","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Audiology and Vestibular Medicine, Senior Department of Otolaryngology, Head and Neck Surgery Chinese PLA Institute of Otolaryngology, the Sixth Medical Center of Chinese PLA General Hospital  Beijing China"},{"name":"National Clinical Research Center for Otolaryngologic Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,4]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","first-page":"S1","article-title":"Clinical Practice Guideline: Sudden Hearing Loss (Update)","volume":"161","author":"Chandrasekhar S. S.","year":"2019","journal-title":"Otolaryngology and Head and Neck Surgery"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820976571"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)62071-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00045"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-023-08361-7"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11894-w"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-024-08789-5"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.0648"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/AUD.0000000000001129"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2022.111400"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1023781"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2021.103027"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28829"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.02.023"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.953265"},{"issue":"6","key":"e_1_2_10_17_1","first-page":"443","article-title":"Guideline of Diagnosis and Treatment of Sudden Deafness (2015)","volume":"50","year":"2015","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_10_18_1","article-title":"Comparable Outcomes in Pediatric and Adult Patients With Sudden Sensorineural Hearing Loss","author":"Shan C.","year":"2026","journal-title":"Laryngoscope"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2010.09.001"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.1072"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31817fdf94"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2024.2598"},{"issue":"6","key":"e_1_2_10_23_1","first-page":"458","article-title":"Clinical Multi\u2010Center Study on the Treatment of Sudden Sensorineural Hearing Loss Accompanied With Feeling of Ear Fullness","volume":"50","author":"Wang X.","year":"2015","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215121002206"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-021-00471-8"},{"issue":"8","key":"e_1_2_10_26_1","first-page":"506","article-title":"Analysis of Clinical Prognosis of Totally Deaf Idiopathic Sudden Sensorineural Hearing Loss in Different Ages","volume":"29","author":"You D.","year":"2023","journal-title":"Alternative Therapies in Health and Medicine"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2023.103878"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.667804"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.422"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2024.2330680"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000004247"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002005"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2020.1813328"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70391","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.70391","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70391","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:11:52Z","timestamp":1781874712000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.70391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/lio2.70391"],"URL":"https:\/\/doi.org\/10.1002\/lio2.70391","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70391"}}