{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:53:20Z","timestamp":1781877200251,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The standard treatment for Zenker's diverticulum (ZD) is transoral septotomy, which has evolved to include techniques such as septal traction to improve outcomes. This study reports the clinical results from our center using a modified transoral septotomy (MTS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 2023 to 2025, 21 patients with ZD were treated with MTS at our center. A dysphagia screening questionnaire was utilized to assess the frequency and severity of dysphagia and regurgitation. All patients underwent a surgical examination, preoperative endoscopy, and preoperative barium swallow. This prospective study aimed to evaluate the outcomes of MTS in treatment\u2010na\u00efve and recurrent ZD cases, highlighting the technique's appeal due to its minimally invasive nature and enhanced patient outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 21 patients (16 males, 5 females, median age 82.5\u2009years, interquartile range (IQR): 61\u201380), symptom scores improved from a median of 12 (IQR: 10\u201316) pre\u2010surgery to 0 (IQR: 0\u20132) post\u2010surgery (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.00001). Post\u2010procedure, 87% of patients were completely asymptomatic, with a total failure rate of 5%. The treatment was successful in 95% of patients overall and in 100% of those with recurrent ZD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Despite inherent study limitations, modified transoral septotomy significantly improves treatment outcomes for ZD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>2 (observational study with significant effect)\u2014Oxford Centre for Evidence\u2010Based Medicine 2011 Levels of Evidence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70392","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T04:15:21Z","timestamp":1775621721000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single\u2010Center Evaluation of Clinical Results After Modified Transoral Septotomy"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9653-9358","authenticated-orcid":false,"given":"Antonio","family":"Martino","sequence":"first","affiliation":[{"name":"Division of Surgery, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Bergamin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Lissandrello","sequence":"additional","affiliation":[{"name":"Department of Medical and Biological Sciences Institute of Diagnostic Radiology, ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Petri","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Santangelo","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Miani","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annarosa","family":"Vasciaveo","sequence":"additional","affiliation":[{"name":"Department of Medical and Biological Sciences Institute of Diagnostic Radiology, ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Uzzau","sequence":"additional","affiliation":[{"name":"DAME, Department of Medicine and Surgery University of Udine  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Berretti","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Del Favero","sequence":"additional","affiliation":[{"name":"Surgical Semi\u2010Intensive, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Rossit","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Vecchiato","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Surgery ASUFC \u201cSanta Maria Della Misericordia\u201d  Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.09.016"},{"issue":"4","key":"e_1_2_9_3_1","first-page":"219","article-title":"Zenker's Diverticulum: Exploring Treatment Options","volume":"33","author":"Bizzotto A.","year":"2013","journal-title":"Acta Othorhinolaryngologica Italica"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.77.910.506"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2009.01036.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doac087"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3267-0"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28030"},{"key":"e_1_2_9_9_1","first-page":"1","article-title":"Long\u2010Term Success of Flexible Endoscopic Septal Division With the Stag Beetle Knife for Zenker's Diverticulum: A Tertiary Center Study","volume":"00","author":"Ishaq S.","year":"2020","journal-title":"Diseases of the Esophagus"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_1226_23"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24846"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(93)90906-X"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000351433"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6918(03)00105-7"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.133.7.695"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200403000-00025"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20247"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-008-0684-7"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-002-8806-x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)03931-0"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011908171"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1244163"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966140"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2261-0"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.12.008"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-007-0191-2"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-025-11746-w"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLE.0000000000000473"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v7.i2.87"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-1945-3"},{"key":"e_1_2_9_32_1","first-page":"46","article-title":"Dilatations of the Oesophagus","volume":"3","author":"Zenker F. A.","year":"1878","journal-title":"Cyclopedia of Practical Medicine"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.70392","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:11:49Z","timestamp":1781874709000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.70392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/lio2.70392"],"URL":"https:\/\/doi.org\/10.1002\/lio2.70392","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2026-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70392"}}