{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:54:34Z","timestamp":1781877274616,"version":"3.54.5"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,4]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n To assess public awareness and interest in retrograde cricopharyngeus dysfunction (R\u2010CPD) in the United States by analyzing trends in internet search behavior.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Using Google Trends, data from Google Search queries from the United States related to R\u2010CPD between January 2013 to May 2024 were obtained. The means of RSV from 2013 to 2018 were compared to RSV from 2019 (when R\u2010CPD was officially defined) to the present. Comparisons of the RSV means between these two periods were performed using paired\n t<\/jats:italic>\n \u2010tests with\n p<\/jats:italic>\n value <\u20090.05 considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Google Trends data from January 2013 through May 2024 were analyzed for 24 R\u2010CPD\u2013related search terms. Mean RSV values from 2013 to 2018 were compared with those from 2019 to 2024, corresponding to the period following formal description of R\u2010CPD. The mean RSV for \u201cR\u2010CPD\u201d increased by 116% (11.5\u2009\u00b1\u20093.9 vs. 24.6\u2009\u00b1\u200915.4;\n p<\/jats:italic>\n \u2009<\u20090.002). Significant increases were also observed for related symptom\u2010based queries, including \u201cwhy can't I burp\u201d (4.3\u2009\u00b1\u20094.8 vs. 17.6\u2009\u00b1\u20094.8;\n p<\/jats:italic>\n \u2009<\u20090.002), \u201ccan't burp\u201d (5.9\u2009\u00b1\u20091.2 vs. 9.3\u2009\u00b1\u20091.6;\n p<\/jats:italic>\n \u2009<\u20090.002), \u201cneed to burp\u201d (35.7\u2009\u00b1\u200910.0 vs. 61.7\u2009\u00b1\u20099.9;\n p<\/jats:italic>\n \u2009<\u20090.002), and \u201cno burp\u201d (10.9\u2009\u00b1\u20094.0 vs. 18.4\u2009\u00b1\u20095.9;\n p<\/jats:italic>\n \u2009<\u20090.002). Across all terms, metropolitan areas demonstrated consistently higher RSVs than broader regional areas.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Search interest related to R\u2010CPD has increased significantly since its formal description, suggesting rising public awareness and information\u2010seeking behavior. Higher search volumes in metropolitan areas may reflect increased recognition, access to specialty care, or disease awareness in urban settings.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/lio2.70425","type":"journal-article","created":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T04:35:40Z","timestamp":1777178140000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Insights Into Retrograde Cricopharyngeus Dysfunction (R\u2010\n CPD<\/scp>\n ) Through Analysis of Internet Search Pattern"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8647-3842","authenticated-orcid":false,"given":"Hardeep S.","family":"Tiwana","sequence":"first","affiliation":[{"name":"Elson S. Floyd College of Medicine at Washington State University Spokane Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang Yu","family":"Gao","sequence":"additional","affiliation":[{"name":"Elson S. Floyd College of Medicine at Washington State University Spokane Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6343-9403","authenticated-orcid":false,"given":"Kevin J.","family":"Fujita\u2010Howie","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology Yale School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Digestive Diseases Yale School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Z.","family":"Lerner","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Otolaryngology Yale School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016\u20105085(87)90445\u20108"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016\u20105085(89)90822\u20106"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440\u20101746.2001.02333.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X19834553"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30346"},{"key":"e_1_2_11_7_1","unstructured":"r\/noburp. accessed [04\/20\/2026] https:\/\/www.reddit.com\/r\/noburp."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2196\/13439"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdata.2023.1132764"},{"key":"e_1_2_11_10_1","unstructured":"Google FAQ about Google Trends data\u2014Trends Help \u201cGoogle FAQ About Google Trends Data\u2014Trends Help \u201d(2019) https:\/\/support.google.com\/trends\/answer\/4365533?hl=en."},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/01455613231162203"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X20917644"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/oto2.70014"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14250"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2196\/17187"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70425","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.70425","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70425","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:11:34Z","timestamp":1781874694000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.70425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/lio2.70425"],"URL":"https:\/\/doi.org\/10.1002\/lio2.70425","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2026-02-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70425"}}