{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T10:45:59Z","timestamp":1782470759678,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K12728"],"award-info":[{"award-number":["24K12728"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Preservation of the facial nerve is critical in surgery for facial nerve schwannoma. Intra\u2010operative monitoring systems typically assess facial nerve function by delivering intermittent electrical stimulation through electrodes; however, this approach cannot effectively achieve continuous stimulation and quantitative assessment. This study aimed to assess the efficacy of a quantitative intra\u2010operative facial nerve continuous monitoring system for preserving post\u2010operative facial nerve function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten patients who underwent continuous nerve monitoring using this system during surgery for facial nerve schwannoma were included. Clinical data, electrode placement sites, and pre\u2010 and postoperative facial nerve function assessed using the House\u2013Brackmann grading system were retrospectively analyzed. In patients with conductive hearing loss, postoperative hearing outcomes were also analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Facial nerve function was preserved in all patients, except for one patient who experienced transient postoperative functional deterioration. In several cases, conductive hearing loss improved following schwannoma resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Continuous and quantitative monitoring of facial nerve function is a reliable intraoperative evaluation that may help prevent unexpected facial nerve injury. This system represents a valuable tool for application in facial nerve schwannoma surgeries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level 4<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70442","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:08:58Z","timestamp":1778850538000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of a Quantitative Intra\u2010Operative Facial Nerve Continuous Monitoring System for Functional Preservation Following Intratemporal Facial Nerve Schwannoma Resection"],"prefix":"10.1002","volume":"11","author":[{"given":"Makoto","family":"Hosoya","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie N.","family":"Shimanuki","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2356-9027","authenticated-orcid":false,"given":"Satoshi","family":"Suda","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Wakabayashi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7136-531X","authenticated-orcid":false,"given":"Takanori","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8204-9518","authenticated-orcid":false,"given":"Naoki","family":"Oishi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1972.00770080651004"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.07.007"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12081789"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2003.09.034"},{"key":"e_1_2_10_6_1","first-page":"694","article-title":"The Many Faces of Facial Nerve Schwannoma","volume":"27","author":"Wiggins R. H.","year":"2006","journal-title":"American Journal of Neuroradiology"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200203000-00004"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2004.09.049"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31938"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26327"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1670687"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000913"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.09.082"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2018.07.013"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820913639"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06765-x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22141"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3171\/2020.6.JNS201548"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2020.1796379"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3171\/2015.3.JNS142677"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-025-09244-9"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.8.JNS132525"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13399"},{"key":"e_1_2_10_24_1","first-page":"488","article-title":"Intraoperative Facial Nerve Monitoring Revealed the Origin of Rapidly Progressing Schwannoma in the Cerebellopontine Angle: A Case of Large Intermediate Nerve Schwannoma","volume":"14","author":"Hosoya M.","year":"2018","journal-title":"Journal of International Advanced Otology"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300202"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1675590"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ons\/opz178"},{"key":"e_1_2_10_28_1","first-page":"5","article-title":"A Review of Facial Nerve Anatomy Seminars in Plastic Surgery: Copyright 2004 by Thieme Medical Publishers","volume":"18","author":"Myckatyn T. M.","year":"2004","journal-title":"Inc 333 Seventh Avenue, New"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/00034894211007241"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318031bc0c"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2013.871746"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70442","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.70442","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.70442","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:47:13Z","timestamp":1782467233000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.70442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,15]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/lio2.70442"],"URL":"https:\/\/doi.org\/10.1002\/lio2.70442","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,15]]},"assertion":[{"value":"2026-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70442"}}