{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:40:37Z","timestamp":1787841637117,"version":"build-2784847793"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate whether a novel body temperature\u2010activated liquid crystal elastomer (LCE) bandage with contraction properties can accelerate wound closure in a porcine model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Adult pigs underwent creation of thirty\u2010six 8\u2010mm circular full\u2010thickness dermal wounds. LCE strips were assembled into bandages and applied to half of the wounds, while the remaining wounds received conventional dressings within the same animal. Wound size was measured over 14\u2009days and expressed as percent wound area relative to baseline. A total of 144 wounds were analyzed across 4 pigs (LCE group,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200972; control group,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200972).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      LCE\u2010treated wounds demonstrated accelerated early reduction in wound area compared with controls (postoperative day [POD] 3: 88.7% vs. 101.5%; POD7: 56.2% vs. 75.0%; POD10: 36.1% vs. 66.7%; all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Although the magnitude of the treatment effect was reduced by POD14, a significant difference remained (44.0% vs. 53.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). No adverse effects were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Liquid crystal elastomer materials show promise as a novel approach for enhancing early dermal wound closure. LCE\u2010based dynamic bandages may have future clinical utility as a noninvasive mechanically active wound dressing platform.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>NA<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70486","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T02:49:58Z","timestamp":1783565398000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Utilizing Dynamic Liquid Crystal Elastomer Dressings to Enhance Early Dermal Wound Closure"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4855-5171","authenticated-orcid":false,"given":"Clifford Jiajun","family":"He","sequence":"first","affiliation":[{"name":"University of California San Diego School of Medicine, University of California\u2014San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7443-0199","authenticated-orcid":false,"given":"Jeffrey D.","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head &amp; Neck Surgery University of California San Diego Health  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Bernard","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head &amp; Neck Surgery University of California San Diego Health  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devyansh","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering, Program of Materials Science and Engineering University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaoweiang","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering, Program of Materials Science and Engineering University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Lee","sequence":"additional","affiliation":[{"name":"University of California San Diego School of Medicine, University of California\u2014San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengqian","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Mechanical and Aerospace Engineering, Program of Materials Science and Engineering University of California, San Diego  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1000-3171","authenticated-orcid":false,"given":"David B.","family":"Hom","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head &amp; Neck Surgery University of California San Diego Health  La Jolla California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00067.2017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580\u2010024\u201000715\u20101"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2011.09.005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13460"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2023.01.003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2023.01.002"},{"issue":"8","key":"e_1_2_10_8_1","first-page":"967","article-title":"How Suture Technique Affects the Cosmetic Outcome of Cutaneous Repairs","volume":"13","author":"Shin T. 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