{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:57:59Z","timestamp":1793113079856,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T00:00:00Z","timestamp":1638576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470729"],"award-info":[{"award-number":["81470729"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Assessment of the hypothesized correlation between the Chinese Velopharyngeal Insufficiency (VPI) Effects on Life Outcomes (VELO) instrument and measured speech parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted in the Oral Clefts Center of West China Hospital of Stomatology between January 2019 and December 2019. Speech parameters including speech intelligibility deficit, VPI severity, VP gap, and need for speech therapy were evaluated by speech\u2010language pathologists. All patients and their parents completed the VELO instrument. The correlation between aforementioned speech parameters and VELO scores was examined utilizing Spearman correlation coefficients. The reliability of VELO test\u2013retest and parent proxy assessment was estimated utilizing intraclass correlation coefficients (ICC). A receiver operating characteristic curve was used to calculate the cutoff VELO score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and forty patients with their parents were enrolled. The mean age was 12.58\u2009\u00b1\u20093.72\u2009years. Both parent and youth VELO total and domain scores recorded moderate to strong correlations with all speech parameters (<jats:italic>r<\/jats:italic>\u2009&gt;\u2009\u2212.40, <jats:italic>P<\/jats:italic> \u02c2\u00a0.001) except the swallowing domain. Most VELO domain items have shown significant correlations with at least one speech parameter. Moreover, the scales of all speech parameters showed different VELO scores (<jats:italic>P<\/jats:italic>\u00a0\u02c2\u00a0.001). The ICC reported test\u2013retest correlation &gt;.73 in all domains, and parent proxy correlation &gt;.63 in most domains except the emotional and perception domains. The cutoff VELO score was 79.04 in parent version and 85.77 in youth version.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The correlations between VELO scores and measured speech parameters have provided evidence for test\u2013retest and parent proxy reliability and criterion and construct validity of the Chinese version of the VELO instrument. A VELO score \u226579.04 (in parent version) or \u226585.77 (in youth version) mostly reflects proper speech\u2010related quality of life. Hence, this instrument could serve as a simple tool to help clinicians understand the social, emotional, and physical influences of VPI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.705","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T13:55:10Z","timestamp":1638626110000},"page":"180-189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Correlation of the Chinese velopharyngeal insufficiency<scp>\u2010related<\/scp> quality of life instrument and speech in subjects with cleft palate"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3793-9084","authenticated-orcid":false,"given":"Karim Ahmed","family":"Sakran","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"},{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Ibb University  Ibb Yemen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remsh Khaled","family":"Al\u2010Rokhami","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, School of Stomatology Lanzhou University  Lanzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Yin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunli","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Alkebsi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"},{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Ibb University  Ibb Yemen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassam Mutahar","family":"Abotaleb","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"},{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Ibb University  Ibb Yemen"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdo Ahmed","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Ibb University  Ibb Yemen"},{"name":"Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Qasem","family":"Al\u2010Watary","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral and 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