{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:40:25Z","timestamp":1787841625785,"version":"build-2784847793"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Describe long\u2010term outcomes of submandibular sialolithiasis treatment, comparing gland\u2010preserving procedures to gland resection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study with prospective patient\u2010reported outcome assessment study included all patients who underwent initial surgical management of submandibular sialolithiasis by a single surgeon from 2013 to 2018. Patients were contacted in 2024 and surveyed regarding treatment response. The primary outcome was xerostomia at long\u2010term follow\u2010up, measured using the Xerostomia Questionnaire (XQ). Secondary outcomes included stone recurrence, postoperative complications, and \u201cultimate surgical success,\u201d defined as resolution of salivary symptoms without additional interventions during the 5\u2010to\u201010\u2010year interval following the initial series of procedures. Eighty\u2010two patients were identified; 36 (43.9%) completed follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 36 respondents (median follow\u2010up 97.4 months), 11 (30.6%) underwent initial gland resection and 25 (69.4%) underwent initial gland\u2010preserving, sialendoscopy\u2010assisted procedures. Among the preservation group, 1 patient required a second gland\u2010preserving procedure, and 3 ultimately underwent gland removal due to persistent symptoms. Resolution of symptoms after the first procedure occurred in all resection patients (100%) and 18 of 25 (72%) in the preservation group. Among those with preserved glands at follow\u2010up (\n                      <jats:italic>n<\/jats:italic>\n                      =\u200922), 6 (27.3%) reported xerostomia (mean XQ 8.0) compared to 4 of 14 (28.6%) in the resection group (mean XQ 3.4). Ultimate surgical success was achieved in 90.9% of the preservation group and 100% of the resection group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both surgical approaches offer durable outcomes, though gland preservation may carry a higher risk of persistent symptoms and potential need for additional intervention. Xerostomia rates were comparable, suggesting gland preservation does not necessarily reduce long\u2010term xerostomia risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>OCEBM Level 4.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70515","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T01:42:12Z","timestamp":1784857332000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Outcomes of Surgical Management for Submandibular Sialolithiasis: Gland Resection Versus Preservation"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3939-2666","authenticated-orcid":false,"given":"Claire","family":"Orth","sequence":"first","affiliation":[{"name":"University of Iowa Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Tannenbaum","sequence":"additional","affiliation":[{"name":"University of Iowa Carver College of Medicine  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeniya","family":"Molotkova","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piper Vander","family":"Waal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailey","family":"Henkle","sequence":"additional","affiliation":[{"name":"Department of Biostatistics University of Iowa College of Public Health  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4486-855X","authenticated-orcid":false,"given":"Henry","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery University of Iowa Hospitals and Clinics  Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"J.HammettandC.Walker \u201cSialolithiasis \u201d National Center for Biotechnology Information (2022) accessed January 30 2024 https:\/\/pubmed.ncbi.nlm.nih.gov\/31751035\/."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2022.07.021"},{"key":"e_1_2_9_4_1","unstructured":"University of Iowa Health Care \u201cSialolithiasis\u2014Salivary Stones: What Causes Them and How to Manage \u201d Iowa Head and Neck Protocols (2023) accessed January 29 2024 https:\/\/medicine.uiowa.edu\/iowaprotocols\/sialolithiasis\u2010salivary\u2010stones\u2010what\u2010causes\u2010them\u2010and\u2010how\u2010manage."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1515\/med\u20102016\u20100081"},{"key":"e_1_2_9_6_1","unstructured":"University of Iowa Health Care \u201cSialolithiasis Radiology \u201d Iowa Head and Neck Protocols (2017) https:\/\/medicine.uiowa.edu\/iowaprotocols\/sialolithiasis\u2010radiology."},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070\u2010013\u20100675\u20101"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392\u2010100x\u20101600"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2009.08.002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.18295\/2075\u20100528.1221"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2017.12.009"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0013.4120"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.23131"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.11.018"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199605\/06)18:3<242::AID-HED6>3.0.CO;2-#"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368\u20108375(00)00063\u20104"},{"issue":"3","key":"e_1_2_9_17_1","first-page":"303","article-title":"Saliva Between Normal and Pathological: Important Factors in Determining Systemic and Oral Health","volume":"2","author":"Iorgulescu G.","year":"2009","journal-title":"Journal of Medicine and Life"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392\u2010100X\u2010suppl.1\u201043\u20102023\u201012"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893\u2010021\u201001462\u20102"}],"container-title":["Laryngoscope Investigative 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