{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:59:55Z","timestamp":1790657995573,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:00:00Z","timestamp":1790553600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Determining operative risk in patients undergoing head and neck free flap surgery has traditionally been difficult. Psoas muscle mass, a proven frailty marker in abdominal surgery, has not been evaluated in this population. This study demonstrates that radiologic sarcopenia and comorbidity burden may identify patients at higher risk for non\u2010home discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective review was performed on 308 patients who underwent head and neck free flap surgery and had preoperative abdominal CT scans between 2014 and 2024. Inverse Psoas Muscle Index (PMI) and Charlson Comorbidity Index (CCI) were analyzed to assess the impact of radiologic sarcopenia and comorbidity on discharge disposition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher inverse PMI had increased odds of discharge non\u2010home (OR 1.37, 95% CI 1.05\u20131.77,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.019). Non\u2010home discharge varied across CCI groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), occurring in 7.4% of patients with mild comorbidity, 39.5% with moderate comorbidity, and 55.7% with high comorbidity. Higher CCI increased odds of discharge non\u2010home (OR 1.30, 95% CI 1.13\u20131.49,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Highest PMI quartile and mild comorbidity resulted in a 100% PPV for discharge home, corresponding to a 0% non\u2010home discharge rate.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lower psoas muscle mass, reflected by higher inverse PMI, independently predicts non\u2010home discharge, supporting its role as a frailty marker in head and neck free flap patients. Patients with higher comorbidity burden, as measured by CCI, have higher odds of non\u2010home discharge. Combining radiologic muscle assessment (inverse PMI) with comorbidity indices demonstrates strong predictive potential for non\u2010home discharge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70580","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:53:43Z","timestamp":1790657623000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Radiologic Sarcopenia and Charlson Comorbidity Index in the Head and Neck Free Flap Population"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1678-035X","authenticated-orcid":false,"given":"Alexandra","family":"Vacaru","sequence":"first","affiliation":[{"name":"Loma Linda University School of Medicine  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4689-819X","authenticated-orcid":false,"given":"Roy W.","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Loma Linda University Health  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4363-3487","authenticated-orcid":false,"given":"Jacob","family":"Hauser","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Medicine  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2392-3309","authenticated-orcid":false,"given":"Elaine","family":"Sun","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Medicine  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyler","family":"Barnett","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Medicine  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Kim","sequence":"additional","affiliation":[{"name":"Loma Linda University School of Medicine  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared C.","family":"Inman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Loma Linda University Health  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021\u20109681(87)90171\u20108"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12635"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2018.11.002"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2016.08.018"},{"issue":"2","key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/SLA.0b013e31826028b1","article-title":"Analytic Morphomics, Core Muscle Size, and Surgical Outcomes","volume":"256","author":"Englesbe M. 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