{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:42:07Z","timestamp":1792420927877,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess post\u2010vaccination changes in chemosensory function among individuals with and without COVID\u201019\u2010related chemosensory impairment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this global, multilingual online survey, participants reported vaccination status, vaccine side effects, and changes in smell and taste before and after each vaccine dose. Responses were collected between May 2022 and August 2023 through convenience sampling. Of 2955 responses, 1352 were included after applying exclusion criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Pfizer\u2010BioNTech accounted for 46.2% of vaccine doses, followed by Sputnik V (16.3%), Moderna (15.4%), AstraZeneca (8.9%), and Sinopharm (7.4%). More than 90% of participants reported no change in general smell or taste following vaccination, regardless of pre\u2010existing chemosensory impairment. Among participants with qualitative chemosensory distortions, improvement was reported by 11%\u201318% for parosmia, 20%\u201329% for phantosmia, and 12%\u201321% for distorted taste, depending on vaccine dose, whereas worsening was reported by 3% or fewer. Side effects varied by vaccine type and were more frequent among individuals reporting worsened chemosensory symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Most participants reported stable smell and taste perception following vaccination. A subset of individuals with qualitative chemosensory distortions reported improvement, while worsening was uncommon.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70589","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T14:01:27Z","timestamp":1792418487000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Post\u2010Vaccination Chemosensory Dysfunction: Changes Following\n                    <scp>SARS<\/scp>\n                    \u2010\n                    <scp>CoV<\/scp>\n                    \u20102 Vaccination in a Global Study"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6886-1961","authenticated-orcid":false,"given":"Sachiko","family":"Koyama","sequence":"first","affiliation":[{"name":"Indiana University School of Medicine  Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Mucignat\u2010Caretta","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine University of Padova  Padova Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9254-8927","authenticated-orcid":false,"given":"Maria A.","family":"Klyuchnikova","sequence":"additional","affiliation":[{"name":"Severtsov Institute of Ecology &amp; Evolution, Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana K.","family":"Laktionova","sequence":"additional","affiliation":[{"name":"Severtsov Institute of Ecology &amp; Evolution, Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Kopishinskaia","sequence":"additional","affiliation":[{"name":"Centre de Recherche du CHU de Qu\u00e9bec, Laval University  Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilya G.","family":"Kvasha","sequence":"additional","affiliation":[{"name":"Severtsov Institute of Ecology &amp; Evolution, Russian Academy of Sciences  Moscow Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpeng","family":"Ye","sequence":"additional","affiliation":[{"name":"Institute for Molecular Bioscience, The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7389-2033","authenticated-orcid":false,"given":"Elena","family":"Cantone","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Reproductive and Dentistry Science, ENT Unit Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shima","family":"Parsa","sequence":"additional","affiliation":[{"name":"Shiraz Institute for Stem Cell &amp; Regenerative Medicine, Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Dolors","family":"Gu\u00e0rdia","sequence":"additional","affiliation":[{"name":"Food Quality and Technology, IRTA\u2010Food Research Institute  Monells Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5144-6956","authenticated-orcid":false,"given":"Valentin","family":"Hivert","sequence":"additional","affiliation":[{"name":"Institute for Molecular Bioscience, The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solal","family":"Chauquet","sequence":"additional","affiliation":[{"name":"Institute for Molecular Bioscience, The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7051-4037","authenticated-orcid":false,"given":"Jingguo","family":"Chen","sequence":"additional","affiliation":[{"name":"The Department of Otolaryngology Head and Neck Surgery Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Centorame","sequence":"additional","affiliation":[{"name":"Institute for Molecular Bioscience, The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0276-7072","authenticated-orcid":false,"given":"Valentina","family":"Parma","sequence":"additional","affiliation":[{"name":"Monell Chemical Senses Center  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Ohla","sequence":"additional","affiliation":[{"name":"Science &amp; 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