{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:41:32Z","timestamp":1792554092289,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated whether fiberoptic endoscopic evaluation of swallowing (FEES)\u2010derived parameters reflect patient\u2010reported dysphagia and swallowing\u2010related quality of life in patients with oropharyngeal squamous cell carcinoma (OPSCC) after surgery\u2010based multimodal therapy with free\u2010flap reconstruction. In addition, it assessed the roles of psychological distress and xerostomia in this context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter, cross\u2010sectional exploratory study included 50 patients. FEES parameters comprised Penetration\u2013Aspiration Scale (PAS) and residue scores. Patient\u2010reported outcomes were assessed using the Sydney Swallow Questionnaire (SSQ) and MD Anderson Dysphagia Inventory (MDADI), psychological distress using the Hospital Anxiety and Depression Scale (HADS), and xerostomia using the Xerostomia Inventory (XI). Associations were examined using Spearman correlations with Benjamini\u2013Hochberg correction and exploratory rank\u2010transformed multiple linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      FEES parameters showed no significant bivariate associations with SSQ or MDADI total scores after correction. HADS and XI showed moderate to strong bivariate associations with SSQ and MDADI. In exploratory multivariable analyses, HADS (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.372,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012) and PAS max (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.318,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) were independently associated with SSQ, whereas XI was not (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.268,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.065). HADS (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.339,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008), XI (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.433,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and PAS max (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.301,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) were independently associated with MDADI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The FEES\u2010derived parameters only partially reflected patient\u2010reported swallowing impairment. These findings support a multidimensional understanding of post\u2010therapeutic dysphagia and suggest routine integration of psychosocial and symptom\u2010oriented assessments into follow\u2010up care in this specific patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>4.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>German Clinical Trials Register (DRKS) Registration Number: DRKS00038870<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lio2.70617","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:12:32Z","timestamp":1792552352000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient\u2010Reported Dysphagia After Multimodal Therapy and Radial Forearm Free\u2010Flap Reconstruction for\n                    <scp>OPSCC<\/scp>\n                    : Associations With\n                    <scp>FEES<\/scp>\n                    Findings, Psychological Distress, and Xerostomia"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0295-5447","authenticated-orcid":false,"given":"Inga Marte Charlott","family":"Seuthe","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5319-4098","authenticated-orcid":false,"given":"Julius Friedrich","family":"Ennenbach","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1267-2790","authenticated-orcid":false,"given":"Natalja","family":"Bolotina","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5548-2604","authenticated-orcid":false,"given":"Nermin","family":"R\u00fcdiger","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Hospitals of the City of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7877-7977","authenticated-orcid":false,"given":"Sabine","family":"Eichhorn","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2456-2169","authenticated-orcid":false,"given":"Eren","family":"Erdogan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3575-6775","authenticated-orcid":false,"given":"Stijn","family":"Bogaert","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, St. Elisabeth\u2010Hospital Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6240-1390","authenticated-orcid":false,"given":"Stefan","family":"Dazert","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, St. Elisabeth\u2010Hospital Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0858-8705","authenticated-orcid":false,"given":"Steffen","family":"Maune","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Hospitals of the City of Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4582-819X","authenticated-orcid":false,"given":"Jonas Jae\u2010Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Catholic Hospital Hagen University of Witten\/Herdecke  Hagen 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