{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:19:14Z","timestamp":1782184754028,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["MOST\u2010110\u20102314\u2010B002\u2010005"],"award-info":[{"award-number":["MOST\u2010110\u20102314\u2010B002\u2010005"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective\/hypothesis<\/jats:title><jats:p>This study correlated audiological results with magnetic resonance (MR) images to predict positive cochlear endolymphatic hydrops (EH) on MR images in patients with Meniere's disease (MD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty definite MD patients with positive cochlear EH on MR images were assigned to Group A. Another 20 definite MD patients with negative cochlear EH on MR images were assigned to Group B. All patients underwent an inner ear test battery followed by MR imaging using HRDROPS\u2010Mi2 technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean hearing levels (MHLs) at frequencies of 125, 250, 500 and 1000\u2009Hz revealed significantly worse in Group A than Group B. Significantly deteriorated MHLs were noted from Grades 0 to II at low frequency (125, 250, and 500\u2009Hz), but not at mid\u2010frequency and high frequency. The respective cutoff hearing thresholds at frequencies of 125, 250, and 500\u2009Hz were 27.5, 32.5, and 40\u2009dBHL, which help predict positive cochlear EH on MR images. By using the sum (27.5\u2009+\u200932.5\u2009+\u200940\u00a0=\u00a0100\u2009dBHL) of cutoff thresholds from three low frequencies as a cutoff value, Group A (80%) showed significantly more ears with sum of low\u2010frequency hearing threshold &gt;100\u2009dBHL than Group B (30%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When sum of three low\u2010frequency (125, 250, and 500\u2009Hz) hearing levels is &gt;100\u2009dBHL, positive cochlear EH may be shown on MR images in definite MD patients. In contrast, those MD patients with sum of three low\u2010frequency hearing levels &lt;100\u2009dBHL, MR imaging should be postponed because resolution of EH may cause negative MR images.<\/jats:p><jats:p><jats:bold>Level of evidence:<\/jats:bold> 4<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.869","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T08:39:51Z","timestamp":1657701591000},"page":"1178-1185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Predicting positive cochlear endolymphatic hydrops on magnetic resonance images"],"prefix":"10.1002","volume":"7","author":[{"given":"Kao\u2010Tsung","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Otolaryngology National Taiwan University Hospital  Taipei 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