{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T21:42:40Z","timestamp":1767908560616,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T00:00:00Z","timestamp":1660953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the rate of surgical site infections (SSI) after pediatric open airway reconstruction using a nationwide database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Cross\u2010sectional study of the American College of Surgeons National Surgical Quality Improvement Program\u2010Pediatric (ACS NSQIP\u2010P) Database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The ACS NSQIP\u2010P was queried for open airway surgeries between 2013 and 2019 determining postoperative SSI and wound dehiscence with a random sample of non\u2010airway cases serving as a control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 637 laryngotracheoplasties (LTP), 411 tracheal resections (TR) and 2100 control procedures were included. LTP and TR were both performed on younger children with more comorbidities than control surgeries (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Postoperative wound complications occurred more often after airway reconstructions than non\u2010airway cases (6.4% vs. 2.9%, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). Compared to non\u2010airway procedures, LTP (OR: 2.42, 95% CI: 1.62\u20133.61) and TR (OR: 2.07, 95% CI: 1.28\u20133.66) developed increased SSI. Multiple logistic regression identified dirty or infected wounds (OR: 4.61, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001, 95% CI: 2.35\u20139.03) and American Society of Anesthesiologists (ASA) Class IV (OR: 3.19, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.02, 95% CI: 1.12\u20138.39) as the strongest predictors of SSI after airway reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SSI after pediatric airway reconstruction occur in 6% of cases and are increased in infected wounds and ASA Class IV surgeries. Recognizing common factors for these complications provide reliable benchmarking to design surgical quality improvement initiatives.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>4.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.895","type":"journal-article","created":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T11:30:01Z","timestamp":1660995001000},"page":"1618-1625","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical site infections after pediatric open airway reconstruction\u2014A National Surgical Quality Improvement Program\u2010Pediatric analysis"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2322-5347","authenticated-orcid":false,"given":"Romaine F.","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Department of Pediatric Otolaryngology Children's Medical Center Dallas  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor","family":"Teplitzky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin M.","family":"Wynings","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6801-7544","authenticated-orcid":false,"given":"Yann\u2010Fuu","family":"Kou","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Department of Pediatric Otolaryngology Children's Medical Center Dallas  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1419-6019","authenticated-orcid":false,"given":"Stephen R.","family":"Chorney","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery University of Texas Southwestern Medical Center  Dallas Texas USA"},{"name":"Department of Pediatric Otolaryngology Children's Medical Center Dallas  Dallas Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2018.07.013"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2018.1495564"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.2067"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0195941700015241"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819832858"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2018.01.017"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.03.023"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2072\u20101439.2016.01.86"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2004.10.019"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2009.03.020"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2017.03.004"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232960"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2008.02.009"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040296"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26165"},{"key":"e_1_2_7_17_1","unstructured":"FDA.Research C for DE and FDA Drug Safety Communication: FDA review results in new warnings about using general anesthetics and sedation drugs in young children and pregnant women 2019.https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-drug-safety-communication-fda-review-results-new-warnings-about-using-general-anesthetics-and"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2018\u20102042"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20102197.2007.04220.x"},{"issue":"5","key":"e_1_2_7_20_1","first-page":"457","article-title":"Surgical site infection: re\u2010assessment of the risk factors","volume":"110","author":"Isik O","year":"2015","journal-title":"Chirurgia (Bucur)"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.14444\/7004"},{"issue":"3","key":"e_1_2_7_22_1","first-page":"360","article-title":"ASA physical status classification is not a good predictor of infection for total knee replacement and is influenced by the presence of comorbidities","volume":"74","author":"Peersman G","year":"2008","journal-title":"Acta Orthop Belg"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.3171\/2016.11.PEDS16454"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2017.089"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2017.107"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.08.035"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010012\u20102256\u20104"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.11.066"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.895","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T06:18:47Z","timestamp":1692685127000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,20]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/lio2.895"],"URL":"https:\/\/doi.org\/10.1002\/lio2.895","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"value":"2378-8038","type":"print"},{"value":"2378-8038","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,20]]},"assertion":[{"value":"2022-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}