{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:46:44Z","timestamp":1789685204457,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Previous small studies have proposed a higher incidence of acute mastoiditis in Israeli pediatric patients than in other Western countries. The aim of this study was to describe the incidence of acute mastoiditis and its epidemiological features over a decade, in order to identify variables that could possibly affect the incidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All admitted patients aged &lt;18\u2009years diagnosed with acute mastoiditis between 2008 and 2018 at Clalit Healthcare Services were identified and a database was generated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1189 and 1115 patients met the inclusion criteria, respectively. Acute mastoiditis diagnosis was confirmed in 95.2% of the patients. The incidence was 7.78 cases per 100,000 children\u2010years but was significantly higher in children under 2\u2009years of age (average of 38.31 per 100,000 children\u2010years). No specific pattern was observed in the annualized incidence rate during the study period. Acute mastoiditis was significantly more common in children of Jewish descent than non\u2010Jewish (10.4 vs. 3.03 per 100,000 children\u2010years, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001) and of high socioeconomic status and is more common in the winter. The prevalence of household parental smoking (52%) was more than double that previously reported in the Israeli population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A higher incidence of acute mastoiditis was observed in the Israeli population than in other reports. The age\u2010dependent rate was identified along with unique epidemiological features such as seasonality, higher incidence in patients of Jewish descent, or high socioeconomic status. Related parental smoking habits lend further support against the exposure of young children to household smoking.<\/jats:p><jats:p>Level of evidence: Individual retrospective cohort study.<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.948","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T10:44:36Z","timestamp":1666003476000},"page":"2139-2144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Epidemiology of pediatric acute mastoiditis in Israel: A National Registry <scp>10\u2010year<\/scp> perspective"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9915-5448","authenticated-orcid":false,"given":"Orit","family":"Samuel","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Carmel Medical Center  Haifa Israel"},{"name":"The Bruce Rappaport Faculty of Medicine The Technion  Haifa Israel"},{"name":"Unit of Otoneurology Lin Medical Center  Haifa Israel"},{"name":"University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Saliba","sequence":"additional","affiliation":[{"name":"The Bruce Rappaport Faculty of Medicine The Technion  Haifa Israel"},{"name":"Department of Community Medicine and Epidemiology Lady Davis Carmel Medical Center  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nili","family":"Stein","sequence":"additional","affiliation":[{"name":"Department of Community Medicine and Epidemiology Lady Davis Carmel Medical Center  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6139-3931","authenticated-orcid":false,"given":"Yotam","family":"Shiner","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Carmel Medical Center  Haifa Israel"},{"name":"The Bruce Rappaport Faculty of Medicine The Technion  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raanan","family":"Cohen\u2010Kerem","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Carmel Medical Center  Haifa Israel"},{"name":"The Bruce Rappaport Faculty of Medicine The Technion  Haifa Israel"},{"name":"Department of Community Medicine and Epidemiology Lady Davis Carmel Medical Center  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.09.007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2012.269"},{"issue":"2","key":"e_1_2_7_4_1","first-page":"455","article-title":"Acute mastoiditis in children: 10\u2009years experience in a French tertiary university referral center","volume":"269","author":"Gorphe P","year":"2012","journal-title":"Eur Arch Oto\u2010Rhino\u2010Laryngol off J Eur Fed Oto\u2010Rhino\u2010Laryngol Soc EUFOS Affil Ger Soc Oto\u2010Rhino\u2010Laryngol \u2010 Head Neck Surg"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.07.002"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200102000-00004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.07.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.05.019"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992280404300307"},{"key":"e_1_2_7_10_1","unstructured":"WHO Vaccine\u2010Preventable Diseases: Monitoring System.Global summary;2020."},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26968"},{"key":"e_1_2_7_12_1","unstructured":"Organisation for Economic Co\u2010operation and Development.Education at a glance 2020: OECD indicators;2020. 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