{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,19]],"date-time":"2024-10-19T04:10:25Z","timestamp":1729311025318,"version":"3.27.0"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T00:00:00Z","timestamp":1667865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Laryngoscope Investig Oto"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To characterize normative adult ranges for cochlear promontory thickness relevant to the development of subendosteal and transpromontory electrodes to rehabilitate various neurotologic disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>Adults (\u226518\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>In vivo radiologic assessment using a 192\u2010slice CT scanner (Force\u2010192; Siemens Healthcare) with ultrahigh\u2010resolution scan mode combined and iterative reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measure<\/jats:title><jats:p>Cochlear promontory thickness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 48 included patients (96 ears), the mean (SD) age was 56 (18) years (range 25\u201394) and included 25 (52%) women. Of that 12 patients (25%) had osteopenia (<jats:italic>n<\/jats:italic>\u00a0=\u00a06) or osteoporosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a06). The mean (SD) body mass index was 28 (5)\u00a0kg\/m<jats:sup>2<\/jats:sup>. The mean (SD) promontory thickness for the 96 temporal bones under study was 1.22 (0.24)\u00a0mm (range 0.55\u20131.85). There was not a statistically significant association between age and promontory thickness (correlation coefficient .08; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.44). Promontory thickness was significantly greater for men than women (mean 1.28 vs. 1.17\u2009mm; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03) and increased with increasing body mass index (correlation coefficient .30; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.004). Last, promontory thickness was significantly less for patients with osteopenia or osteoporosis compared with those without these conditions (mean 1.09 vs. 1.27\u2009mm; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cochlear promontory thickness can vary by almost 1.5\u2009mm across patients and is significantly associated with patient sex, body mass index, and comorbid osteopenia\/osteoporosis. Subendosteal and transpromontory electrode placement techniques must account for this degree of variability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence<\/jats:title><jats:p>IV<\/jats:p><\/jats:sec>","DOI":"10.1002\/lio2.965","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T12:51:13Z","timestamp":1667911873000},"page":"2084-2087","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cochlear promontory anatomy relevant to development of subendosteal and transpromontory electrodes using 192\u2010section ultra\u2010high resolution temporal bone CT imaging"],"prefix":"10.1002","volume":"7","author":[{"given":"John P.","family":"Marinelli","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil S.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2010Head and Neck Surgery, Department of Surgery University of Utah  Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine M.","family":"Lohse","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John I.","family":"Lane","sequence":"additional","affiliation":[{"name":"Department of Radiology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew L.","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Mayo Clinic  Rochester Minnesota USA"},{"name":"Department of Neurologic Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480601075423"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003529"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000169779.54162.34"},{"key":"e_1_2_8_5_1","first-page":"1375","article-title":"Would an endosteal CI\u2010electrode make sense? Comparison of the auditory nerve excitability from different stimulation sites using ESRT measurements and mathematical models","volume":"271","author":"Pau HW","year":"2014","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-022-03271-4"},{"key":"e_1_2_8_7_1","first-page":"337","article-title":"Current understanding of osteoporosis according to the position of the World Health Organization (WHO) and international osteoporosis foundation","volume":"9","author":"Czerwinski E","year":"2007","journal-title":"Ortop Traumatol Rehabil"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4338"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4802730"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-022-03161-x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-018-0505-2"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-020-1452-y"}],"container-title":["Laryngoscope Investigative Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.965","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/lio2.965","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/lio2.965","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T12:55:04Z","timestamp":1729256104000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/lio2.965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,8]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1002\/lio2.965"],"URL":"https:\/\/doi.org\/10.1002\/lio2.965","archive":["Portico"],"relation":{},"ISSN":["2378-8038","2378-8038"],"issn-type":[{"type":"print","value":"2378-8038"},{"type":"electronic","value":"2378-8038"}],"subject":[],"published":{"date-parts":[[2022,11,8]]},"assertion":[{"value":"2022-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}